NOC41_XENLA
ID NOC41_XENLA Reviewed; 526 AA.
AC Q6NRQ2;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Nucleolar complex protein 4 homolog A;
DE Short=NOC4 protein homolog A;
DE AltName: Full=NOC4-like protein A;
DE AltName: Full=Nucleolar complex-associated protein 4-like protein A;
GN Name=noc4l-a;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250|UniProtKB:Q9BVI4};
CC Multi-pass membrane protein {ECO:0000255}. Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9BVI4}.
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family. {ECO:0000305}.
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DR EMBL; BC070683; AAH70683.1; -; mRNA.
DR RefSeq; NP_001084831.1; NM_001091362.1.
DR AlphaFoldDB; Q6NRQ2; -.
DR SMR; Q6NRQ2; -.
DR DNASU; 431875; -.
DR GeneID; 431875; -.
DR KEGG; xla:431875; -.
DR CTD; 431875; -.
DR Xenbase; XB-GENE-6251758; noc4l.S.
DR OrthoDB; 891751at2759; -.
DR Proteomes; UP000186698; Chromosome 1S.
DR Bgee; 431875; Expressed in neurula embryo and 19 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR027193; Noc4.
DR PANTHER; PTHR12455; PTHR12455; 1.
DR Pfam; PF03914; CBF; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 2: Evidence at transcript level;
KW Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..526
FT /note="Nucleolar complex protein 4 homolog A"
FT /id="PRO_0000173489"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 526 AA; 60621 MW; FC7388FAEEFAC1B7 CRC64;
MAARKTKHAC RIQDKRSDAE RQDLDTKLAA VLESRGNANA VFDILEHLES KKEEVVQAAI
RTASKLFEVM LEKRELYIGD LPAENGTLPD TYSAEDKYKM WMRHRYNSCA ACILDLLQHS
SFSNQELALC TLMKFIQLEG KFPLENSEWK DSYRFPRELL KFVIDNLLQE EADCTLLITR
FQEYLEYDDV RYYTMTVTND CVSRVQQKNK LVLPPVFQTN VFCLLSSINI PVEESALGNF
LVTKNVNNED WKPSKLKDHK RVFERVWMIF LKHQLSVSLY KKVLLILHES ILPHMSKPTL
MIDFLTAAYD VGGAISLLAL NGLFILIHQH NLEYPDFYKK LYSLLEPSIF HVKYRARFFH
LANMFLSSTH LPVYLVAAFA KRLARLALTA PPQVLLMIIP FICNLIRRHP ACRVLIHRPS
AGDLATDPYI MEEQDPAKSQ ALESSLWELE VLQQHYHGDV VRAANVISRP LSAQESDISG
LLEISSCELY DKEMKKKKFK SVPLEYEPVR GLLGLKSDIT AQHFTF