NOC4B_XENLA
ID NOC4B_XENLA Reviewed; 525 AA.
AC Q6NU91;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Nucleolar complex protein 4 homolog B;
DE Short=NOC4 protein homolog B;
DE AltName: Full=NOC4-like protein B;
DE AltName: Full=Nucleolar complex-associated protein 4-like protein B;
GN Name=noc4l-b;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250|UniProtKB:Q9BVI4};
CC Multi-pass membrane protein {ECO:0000255}. Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9BVI4}.
CC -!- SIMILARITY: Belongs to the CBF/MAK21 family. {ECO:0000305}.
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DR EMBL; BC068706; AAH68706.1; -; mRNA.
DR RefSeq; NP_001084692.1; NM_001091223.1.
DR AlphaFoldDB; Q6NU91; -.
DR SMR; Q6NU91; -.
DR PRIDE; Q6NU91; -.
DR DNASU; 414653; -.
DR GeneID; 414653; -.
DR KEGG; xla:414653; -.
DR CTD; 414653; -.
DR Xenbase; XB-GENE-6252284; noc4l.L.
DR OMA; DVRYYTF; -.
DR OrthoDB; 891751at2759; -.
DR Proteomes; UP000186698; Chromosome 1L.
DR Bgee; 414653; Expressed in oocyte and 19 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR005612; CCAAT-binding_factor.
DR InterPro; IPR027193; Noc4.
DR PANTHER; PTHR12455; PTHR12455; 1.
DR Pfam; PF03914; CBF; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 2: Evidence at transcript level;
KW Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..525
FT /note="Nucleolar complex protein 4 homolog B"
FT /id="PRO_0000173490"
FT TRANSMEM 307..327
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..406
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 60494 MW; 5C280C749FA49044 CRC64;
MAARKAKHAF RSQATQSDAE RQDLDSKLAA VLESRGNANA VFDILEHLES KKEDVVQAAI
RTTSKLFEVL LEKRELYIGD LPAEDDSPPD TCSAEDKYKM WMRNRYNSCV SCLLDLLQYS
SFSVQELVLC TLMKFIQLEG KFPLENSEWR DSYRFPRELL KFVVDNLLQE EADCTLLITR
FQEYLEYDDV RYYTMTVTTE CVSRIQQKNK QVLPPVFQTN VFCLLSSINM PVEESTLGNF
LVTKNENHEE WKPSKLKEQK RVFERVWMSF LKHQLSVSLY KKVLLILHES ILPHMSKPSL
MIDFLTAAYD VGGAISLLAL NGLFILIHQH NLEYPDFYKK LYSLLEPSVF HVKYRARFFH
LANLFLSSTH LPVYLVAAFA KRLARLALTA PPQVLLMIIP FICNLIRRHP ACRVLIHRPS
AGDLVTDPYI MEEQDPAKSQ ALESCLWELE VLQQHYHGDV VRAANVISRA LSAQESDVSG
LLEMSSCELF DKEMKKKFKS VPLEYEPVRG LLGLKSDITA EHFTF