ID   NOC4L_DANRE             Reviewed;         525 AA.
AC   Q4VBT2;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Nucleolar complex protein 4 homolog;
DE            Short=NOC4 protein homolog;
DE   AltName: Full=NOC4-like protein;
DE   AltName: Full=Nucleolar complex-associated protein 4-like protein;
GN   Name=noc4l; ORFNames=zgc:110429;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000250|UniProtKB:Q9BVI4};
CC       Multi-pass membrane protein {ECO:0000255}. Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9BVI4}.
CC   -!- SIMILARITY: Belongs to the CBF/MAK21 family. {ECO:0000305}.
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DR   EMBL; BC095257; AAH95257.1; -; mRNA.
DR   RefSeq; NP_001019568.1; NM_001024397.1.
DR   AlphaFoldDB; Q4VBT2; -.
DR   SMR; Q4VBT2; -.
DR   STRING; 7955.ENSDARP00000067000; -.
DR   PaxDb; Q4VBT2; -.
DR   GeneID; 554096; -.
DR   KEGG; dre:554096; -.
DR   CTD; 79050; -.
DR   ZFIN; ZDB-GENE-050522-98; noc4l.
DR   eggNOG; KOG2154; Eukaryota.
DR   InParanoid; Q4VBT2; -.
DR   OrthoDB; 891751at2759; -.
DR   PhylomeDB; Q4VBT2; -.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   PRO; PR:Q4VBT2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030692; C:Noc4p-Nop14p complex; IBA:GO_Central.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR   InterPro; IPR005612; CCAAT-binding_factor.
DR   InterPro; IPR027193; Noc4.
DR   PANTHER; PTHR12455; PTHR12455; 1.
DR   Pfam; PF03914; CBF; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..525
FT                   /note="Nucleolar complex protein 4 homolog"
FT                   /id="PRO_0000173488"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   525 AA;  60726 MW;  A77F45BD8484083D CRC64;
     MAPSGDSNVK EHNNQVSYKK AINTKTDLIL QNKKHANDIF DVIEYLQSEK EKEIIFATNA
     CSKIFCELIE RGDLFVGELP KEEDLAQGDR SAEEKYHIFM RHRYNSCVEL MLENVSHESF
     QVKETSLCAV MKFVATEGKH PLQNLDWSEH YNFPRELIQA LVEHLLSEKE DMSLLISRFQ
     EFMEKDDVRY YVMSSVRYST ATVMERNKKA VIPVFQNNVF NLLTTINIPN QASEMTNFLV
     QQQSKHDDWK AAKLKEHKRA FEQMWLLFLR YKLPGSMYKK ILVILHESIL PQMSDPKLMM
     DFLSAAYDIG GAISLSALNG LFVPIHEHNL DYPDFYKKLY NLLDPSIFHV KYRARFFHLA
     NIFLSSTHLP VYLVAAFVKR LARLSLTAPP TALLILLPFI CNLIRRHPSC RVLIHRPSAA
     DEPCDDPYVM EEEDPAQCHA LESSLWEIKT LQNHHHPDVS KAATMINEPL SAQEEDISEL
     LELTTFELME RELKGEKKTV PLEFDMATDL LKSSREVLGV HFTLE