ID   NOCM_AGRFC              Reviewed;         241 AA.
AC   P35113;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Nopaline transport system permease protein NocM;
GN   Name=nocM; OrderedLocusNames=Atu6025; ORFNames=AGR_pTi_65;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1732218; DOI=10.1128/jb.174.3.841-849.1992;
RA   Zanker H., von Lintig J., Schroeder J.;
RT   "Opine transport genes in the octopine (occ) and nopaline (noc) catabolic
RT   regions in Ti plasmids of Agrobacterium tumefaciens.";
RL   J. Bacteriol. 174:841-849(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- FUNCTION: Component of the nopaline active transport system probably
CC       consisting of four subunits: Q, M, P and T. This system is also capable
CC       of transporting octopine provided that catabolic functions are induced
CC       with nopaline.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. HisMQ subfamily. {ECO:0000305}.
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DR   EMBL; M77785; AAA50513.1; -; Genomic_DNA.
DR   EMBL; AE007871; AAK90983.1; -; Genomic_DNA.
DR   PIR; AG3230; AG3230.
DR   PIR; F42600; F42600.
DR   RefSeq; NP_396542.1; NC_003065.3.
DR   RefSeq; WP_003523894.1; NC_003065.3.
DR   AlphaFoldDB; P35113; -.
DR   SMR; P35113; -.
DR   TCDB; 3.A.1.3.6; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; AAK90983; AAK90983; Atu6025.
DR   KEGG; atu:Atu6025; -.
DR   PATRIC; fig|176299.10.peg.5232; -.
DR   HOGENOM; CLU_019602_1_4_5; -.
DR   OMA; FFQNAWY; -.
DR   PhylomeDB; P35113; -.
DR   BioCyc; AGRO:ATU6025-MON; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071705; P:nitrogen compound transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR01726; HEQRo_perm_3TM; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Plasmid; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..241
FT                   /note="Nopaline transport system permease protein NocM"
FT                   /id="PRO_0000060123"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          17..215
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   241 AA;  26424 MW;  390E7B6C070C5D65 CRC64;
     MDIQLIIESF PKLLAAVPTT LTLAFISLLI GFVVSVPVAL MRLSKNRIVS SLAYGYVYII
     RSTPLLVQMF LIYYGSAQFR GVLSEVGLWS SFREPWFCAI LALALNTAAY TSEIIRGGIQ
     SVSLGQIEAA RAVGMSTFLQ FRRIVFPIAI RQALPAYGNE VMLIIKSTSL ASTITIVEVT
     GLAKQIISAT YSPVEVFIVA GAIYLFITFV VSRLVMLAEW WLNPHMRARV GGTAPKAAET
     H