ID   NOCR_AGRFC              Reviewed;         300 AA.
AC   Q00678;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Regulatory protein NocR;
GN   Name=nocR; OrderedLocusNames=Atu6029; ORFNames=AGR_pTi_70;
OS   Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS   (strain C58)).
OG   Plasmid pTiC58.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC   Agrobacterium tumefaciens complex.
OX   NCBI_TaxID=176299;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1799698; DOI=10.1094/mpmi-4-370;
RA   von Lintig J., Zanker H., Schroeder J.;
RT   "Positive regulators of opine-inducible promoters in the nopaline and
RT   octopine catabolism regions of Ti plasmids.";
RL   Mol. Plant Microbe Interact. 4:370-378(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11743193; DOI=10.1126/science.1066804;
RA   Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA   Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA   Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA   Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA   Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA   Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA   Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA   Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA   Gordon M.P., Olson M.V., Nester E.W.;
RT   "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT   C58.";
RL   Science 294:2317-2323(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C58 / ATCC 33970;
RX   PubMed=11743194; DOI=10.1126/science.1066803;
RA   Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA   Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA   Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA   Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA   Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT   "Genome sequence of the plant pathogen and biotechnology agent
RT   Agrobacterium tumefaciens C58.";
RL   Science 294:2323-2328(2001).
CC   -!- FUNCTION: Positive regulatory protein for the noc operon involved in
CC       nopaline catabolism and uptake.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA50519.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAK90987.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M65107; AAA50519.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE007871; AAK90987.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_396546.3; NC_003065.3.
DR   RefSeq; WP_065702830.1; NC_003065.3.
DR   AlphaFoldDB; Q00678; -.
DR   SMR; Q00678; -.
DR   DNASU; 1137352; -.
DR   EnsemblBacteria; AAK90987; AAK90987; Atu6029.
DR   KEGG; atu:Atu6029; -.
DR   PATRIC; fig|176299.10.peg.5236; -.
DR   HOGENOM; CLU_039613_6_3_5; -.
DR   OMA; LLHGHFD; -.
DR   Proteomes; UP000000813; Plasmid Ti.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08415; PBP2_LysR_opines_like; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037424; NocR_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Plasmid; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..300
FT                   /note="Regulatory protein NocR"
FT                   /id="PRO_0000105694"
FT   DOMAIN          1..59
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        19..38
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   300 AA;  32916 MW;  F8DE2C86C08F0B5F CRC64;
     MIQSRQLEAF RAVMLTGGMT SAANLVRITQ PAISRLIRDL EEEIGISLFE RTGNRLRPTR
     EAGILFKEVS RHFNGIQHID KVAAELKKSH MGSLRVACYT APALSFMSGV IQTFIADRPD
     VSVYLDTVPS QTVLELVSLQ HYDLGISILA GDYPGLTTEP VPSFRAVCLL PPGHRLEDKE
     TVHATDLEGE SLICLSPVSL LRMQTDAALD SCGVHCNRRI ESSLALNLCD LVSRGMGVGI
     VDPFTADYYS ANPVIQRSFD PVVPYHFAIV LPTDSPPPRL VSEFRAALLD ALKALPYETI