NODA_RHIME
ID NODA_RHIME Reviewed; 196 AA.
AC P02962; O52476; Q52970;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Nodulation protein A;
DE EC=2.3.1.-;
GN Name=nodA; OrderedLocusNames=RA0475; ORFNames=SMa0869;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OG Plasmid pSymA (megaplasmid 1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=4006668; DOI=10.1089/dna.1985.4.241;
RA Egelhoff T.T., Fisher R.F., Jacobs T.W., Mulligan J.T., Long S.R.;
RT "Nucleotide sequence of Rhizobium meliloti 1021 nodulation genes: nodD is
RT read divergently from nodABC.";
RL DNA 4:241-248(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=41;
RX PubMed=6336331; DOI=10.1093/nar/12.24.9509;
RA Toeroek I., Kondorosi E., Stepkowski T., Posfai J., Kondorosi A.;
RT "Nucleotide sequence of Rhizobium meliloti nodulation genes.";
RL Nucleic Acids Res. 12:9509-9524(1984).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=042B;
RA Yang X., Gao W.M., Yang S.S.;
RT "The complete sequence of S. meliloti 042B nodABC.";
RL Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481432; DOI=10.1073/pnas.161294798;
RA Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA Long S.R.;
RT "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT meliloti pSymA megaplasmid.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
RN [6]
RP CHARACTERIZATION.
RX PubMed=8930915; DOI=10.1046/j.1365-2958.1996.00069.x;
RA Debelle F., Plazanet C., Roche P., Pujol C., Savagnac A., Rosenberg C.,
RA Prome J.-C., Denarie J.;
RT "The NodA proteins of Rhizobium meliloti and Rhizobium tropici specify the
RT N-acylation of Nod factors by different fatty acids.";
RL Mol. Microbiol. 22:303-314(1996).
CC -!- FUNCTION: N-acyltransferase required for nodulation. Acts in the
CC production of a small, heat-stable compound (nod) that stimulates
CC mitosis in various plant protoplasts. The N-acyl substituent is a C16
CC unsaturated or an omega-1 hydroxylated fatty acid in R.meliloti.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- SIMILARITY: Belongs to the NodA family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA25807.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; X01649; CAA25808.1; -; Genomic_DNA.
DR EMBL; X01649; CAA25807.1; ALT_INIT; Genomic_DNA.
DR EMBL; M11268; AAA98360.1; -; Genomic_DNA.
DR EMBL; AF038577; AAB95328.1; -; Genomic_DNA.
DR EMBL; AE006469; AAK65133.1; -; Genomic_DNA.
DR PIR; A03480; ZZZRAM.
DR PIR; A03481; ZZZRA4.
DR PIR; C95321; C95321.
DR RefSeq; NP_435721.1; NC_003037.1.
DR RefSeq; WP_010967455.1; NC_003037.1.
DR AlphaFoldDB; P02962; -.
DR EnsemblBacteria; AAK65133; AAK65133; SMa0869.
DR GeneID; 61599277; -.
DR KEGG; sme:SMa0869; -.
DR PATRIC; fig|266834.11.peg.486; -.
DR HOGENOM; CLU_098284_0_0_5; -.
DR OMA; FPIGRPM; -.
DR Proteomes; UP000001976; Plasmid pSymA.
DR GO; GO:0005829; C:cytosol; IEA:InterPro.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00084; NodA; 1.
DR InterPro; IPR003484; NodA.
DR InterPro; IPR020567; Nodulation_prot_NodA_CS.
DR Pfam; PF02474; NodA; 1.
DR TIGRFAMs; TIGR04245; nodulat_NodA; 1.
DR PROSITE; PS01349; NODA; 1.
PE 1: Evidence at protein level;
KW Acyltransferase; Cytoplasm; Nodulation; Plasmid; Reference proteome;
KW Transferase.
FT CHAIN 1..196
FT /note="Nodulation protein A"
FT /id="PRO_0000196342"
FT VARIANT 87
FT /note="E -> K (in strain: 042B)"
FT CONFLICT 115..116
FT /note="EL -> AI (in Ref. 2; AAA98360)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 196 AA; 21837 MW; EFC3C9A11D84ED38 CRC64;
MSLKVQWKLC WENQLERADH QELSEFFRKS YGPTGAFHAK PFEGGRSWAG ARPERRAIAY
DSVGIASHMG VLRRFIKVGE TDLLVAELGL YAVRPDLERM GIAHSVGALT PTLRELGVPF
AFGTVRHAMR NHVERYCQNG MASILTGVRV RSSIAEVNAD LPSTRTEDPL VVIFPVGRPL
NEWPPGTLIE RNGSEL
