NODC_RHIME
ID NODC_RHIME Reviewed; 426 AA.
AC P04341;
DT 20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=N-acetylglucosaminyltransferase;
DE EC=2.4.1.-;
DE AltName: Full=Nodulation protein C;
GN Name=nodC; OrderedLocusNames=RA0473; ORFNames=SMa0866;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OG Plasmid pSymA (megaplasmid 1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=2985535; DOI=10.1128/jb.162.2.469-476.1985;
RA Jacobs T.W., Egelhoff T.T., Long S.R.;
RT "Physical and genetic map of a Rhizobium meliloti nodulation gene region
RT and nucleotide sequence of nodC.";
RL J. Bacteriol. 162:469-476(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=41;
RX PubMed=6336331; DOI=10.1093/nar/12.24.9509;
RA Toeroek I., Kondorosi E., Stepkowski T., Posfai J., Kondorosi A.;
RT "Nucleotide sequence of Rhizobium meliloti nodulation genes.";
RL Nucleic Acids Res. 12:9509-9524(1984).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481432; DOI=10.1073/pnas.161294798;
RA Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA Long S.R.;
RT "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT meliloti pSymA megaplasmid.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- FUNCTION: Involved in the synthesis of Nod factor, a sulfated N-acyl-
CC beta-1,4-tetrasaccharide of N-acetylglucosamine which initiates a
CC series of events in the host plant species leading eventually to
CC nodulation.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Peripheral membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NodC/HAS family. {ECO:0000305}.
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DR EMBL; X01649; CAA25810.1; -; Genomic_DNA.
DR EMBL; M11268; AAA98362.1; -; Genomic_DNA.
DR EMBL; AE006469; AAK65131.1; -; Genomic_DNA.
DR PIR; A03487; ZZZRC4.
DR PIR; A95321; A95321.
DR RefSeq; NP_435719.1; NC_003037.1.
DR RefSeq; WP_010967454.1; NC_003037.1.
DR AlphaFoldDB; P04341; -.
DR SMR; P04341; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR EnsemblBacteria; AAK65131; AAK65131; SMa0866.
DR GeneID; 61599275; -.
DR KEGG; sme:SMa0866; -.
DR PATRIC; fig|266834.11.peg.484; -.
DR HOGENOM; CLU_029695_4_2_5; -.
DR OMA; DVIVPCF; -.
DR Proteomes; UP000001976; Plasmid pSymA.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR026463; Chitooligosach_Synthase_NodC.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
DR TIGRFAMs; TIGR04242; nodulat_NodC; 1.
PE 3: Inferred from homology;
KW Cell membrane; Glycosyltransferase; Membrane; Nodulation; Plasmid;
KW Reference proteome; Transferase.
FT CHAIN 1..426
FT /note="N-acetylglucosaminyltransferase"
FT /id="PRO_0000197192"
FT REGION 401..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 39
FT /note="A -> S (in strain: 41)"
FT VARIANT 166
FT /note="M -> V (in strain: 41)"
SQ SEQUENCE 426 AA; 46769 MW; 5C9457E6154E9415 CRC64;
MYLLDTTSTA AISIYALLLT AYRSMQVLYA RPIDGPAVAA EPVETRPLPA VDVIVPSFNE
DPGILSACLA SIADQDYPGE LRVYVVDDGS RNREAIVRVR AFYSRDPRFS FILLPENVGK
RKAQIAAIGQ SSGDLVLNVD SDSTIAFDVV SKLASKMRDP EVGAVMGQLT ASNSGDTWLT
KLIDMEYWLA CNEERAAQSR FGAVMCCCGP CAMYRRSALA SLLDQYETQL FRGKPSDFGE
DRHLTILMLK AGFRTEYVPD AIVATVVPDT LKPYLRQQLR WARSTFRDTF LALPLLRGLS
PFLAFDAVGQ NIGQLLLALS VVTGLAHLIM TATVPWWTIL IIACMTIIRC SVVALHARQL
RFLGFVLHTP INLFLILPLK AYALCTLSNS DWLSRYSAPE VPVSGGKQTP IQTSGRVTPD
CTCSGE
