ID   NODD1_BRAJP             Reviewed;         321 AA.
AC   P12232;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Nodulation protein D 1;
GN   Name=nodD1;
OS   Bradyrhizobium japonicum.
OG   Plasmid sym.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=375;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=USDA 191;
RX   PubMed=2826389; DOI=10.1128/jb.170.1.12-20.1988;
RA   Appelbaum E.R., Thompson D.V., Idler K., Chartrain N.;
RT   "Rhizobium japonicum USDA 191 has two nodD genes that differ in primary
RT   structure and function.";
RL   J. Bacteriol. 170:12-20(1988).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; M18971; AAA26334.1; -; Genomic_DNA.
DR   PIR; A28663; A28663.
DR   AlphaFoldDB; P12232; -.
DR   SMR; P12232; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Plasmid; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..321
FT                   /note="Nodulation protein D 1"
FT                   /id="PRO_0000105704"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   321 AA;  36388 MW;  2EF16B63A8E00284 CRC64;
     MRFKGLDLNL LVALDALMTE RKLTAAARSI NLSQPAMSAA ITRLRTYFRD ELFTMNGREL
     VPTPRAEALA PAVREALLHI HLSIISWDPF NPAQSDRSFR IILSDFMTLM FFERVVVRVA
     REAPAVSFEL LPFSDEPDEL LRRGDVDFLI LPEMFMSHTH PRAKLFDERF VCVSCPTNQK
     LPPQLSIDNY VSMGHVAAQF GKQRPSVEEW LLREHGLRRR VEVAVPGFTM IPPFLSGTDR
     IATLPLRLAM HFAKAIPLRI TELPQPIFPA FTEAVQWPAP HSSDPASLWM REIFLQEASR
     VEFQSETSAH ALSSSQLPTC L