ID   NODD1_BRASN             Reviewed;         314 AA.
AC   P50327;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Nodulation protein D 1;
GN   Name=nodD1;
OS   Bradyrhizobium sp. (strain NC92).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=55395;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8631662; DOI=10.1128/jb.178.10.2757-2766.1996;
RA   Gillette W.K., Elkan G.H.;
RT   "Bradyrhizobium (Arachis) sp. strain NC92 contains two nodD genes involved
RT   in the repression of nodA and a nolA gene required for the efficient
RT   nodulation of host plants.";
RL   J. Bacteriol. 178:2757-2766(1996).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- MISCELLANEOUS: There are at least two nodD genes in B.sp strain NC92.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U33192; AAB06562.1; -; Genomic_DNA.
DR   AlphaFoldDB; P50327; -.
DR   SMR; P50327; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..314
FT                   /note="Nodulation protein D 1"
FT                   /id="PRO_0000105707"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   314 AA;  35827 MW;  62F3A8AAC77EB788 CRC64;
     MRFKGLDLNL LVALDALMTE RNLTAAARKI HLSQPAMSAA VARLRTYFGD ELFTMRGREL
     VPTPRAEGLA APIREALLHI QLSIISRDAF DPAESSRRFR IILSDFMTIV FFRRIIDRVA
     REAPAVRFEL LPFSDEHDEL LRRGEVDFLV FPELFMSSAH PKATLFEETL VCVGCRTNKQ
     LSRQLTVEKY MSMGHVAAKF GRALRPNIEE WFLLEHGLKR RIEVVVQGFG MIPPVLVDTV
     RIGTMPLRLA KHFEKQMLLK IVEPPLPLPS FTEAVQWPAA KNTDPASIWM RRIILQEAAN
     MASAHEAARH RRHC