ID   NODD2_BRAEL             Reviewed;         331 AA.
AC   P50324;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Nodulation protein D 2;
GN   Name=nodD2;
OS   Bradyrhizobium elkanii.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=29448;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=USDA 94;
RX   PubMed=7949325; DOI=10.1094/mpmi-7-0564;
RA   Dobert R.C., Breil B.T., Triplett E.W.;
RT   "DNA sequence of the common nodulation genes of Bradyrhizobium elkanii and
RT   their phylogenetic relationship to those of other nodulating bacteria.";
RL   Mol. Plant Microbe Interact. 7:564-572(1994).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- MISCELLANEOUS: There are at least two nodD genes in B.elkanii.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U04609; AAA63597.1; -; Genomic_DNA.
DR   RefSeq; WP_016848463.1; NZ_SEMA01000027.1.
DR   AlphaFoldDB; P50324; -.
DR   SMR; P50324; -.
DR   GeneID; 66429409; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..331
FT                   /note="Nodulation protein D 2"
FT                   /id="PRO_0000105702"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   331 AA;  37362 MW;  6DC8311634DF5BCD CRC64;
     MRFNGLDLNL LVALDALMTE RSLTAAARKI NLSQPAMSAA VARLRSYFRD ELFAMRGRKL
     VPTSRAEGLA APVREALMHI ELSIIARDAF DPAQSNRRFR IGLCDFITIV FFRHVAERVA
     REAPAVSFEL VALADEHDEL LRRGELDFII LPEPFMSSAH PRIALFEERL VCVGCGTNGE
     LRRRLTFDRY MTMGHVAVKL GVARMPPIEE SFLLDRGLNR RIDILVHSYG MIPPMLMGTS
     RIGTMPLRLV KHFETTMPLR IAELPRPFPT FTEAVQWPVL QNSDPESIWM REILLQEAAR
     MTSTSDDCSM SYASEQADTE GRLTSVASRL S