ID   NODD2_BRASN             Reviewed;         337 AA.
AC   P50328;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Nodulation protein D 2;
GN   Name=nodD2;
OS   Bradyrhizobium sp. (strain NC92).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=55395;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8631662; DOI=10.1128/jb.178.10.2757-2766.1996;
RA   Gillette W.K., Elkan G.H.;
RT   "Bradyrhizobium (Arachis) sp. strain NC92 contains two nodD genes involved
RT   in the repression of nodA and a nolA gene required for the efficient
RT   nodulation of host plants.";
RL   J. Bacteriol. 178:2757-2766(1996).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- MISCELLANEOUS: There are at least two nodD genes in B.sp strain NC92.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U33192; AAB06563.1; -; Genomic_DNA.
DR   AlphaFoldDB; P50328; -.
DR   SMR; P50328; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..337
FT                   /note="Nodulation protein D 2"
FT                   /id="PRO_0000105708"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   337 AA;  38142 MW;  7645884AB5160177 CRC64;
     MRFKGLDLNL LVVLDSLMTA RNLTAAARSI NLSQPAMSAA VARLRAYFGD ELFTMRGRTL
     VPTPRAESLA SPVRKALLDI QLSIIARDKF NPAESCRRFR ISLSDCVTLI FFRQIVDRVA
     RDAPAVSFEL LPLREDHDEL LRRGEIDFLI MPEPFMSSAH PRAALFGERL VCAGCRTNKR
     LPHRLTFEEY MSLGQVAVRW NLAHNPSIEE QFLLQHGLKR RIDIVVQSFC MIPPMLSGTD
     RIGVMPLRLV KHFEKVTPLR IVDLPLSLPA FTEAVQWPAF HNADPASIWM REILLQESSR
     MGSWGEERQT VKSLLSSNLR SDPLCIKASQ LAEPRSS