ID   NODD2_RHITR             Reviewed;         314 AA.
AC   P32008;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Nodulation protein D 2;
GN   Name=nodD2;
OS   Rhizobium tropici.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=398;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8419293; DOI=10.1128/jb.175.2.438-447.1993;
RA   van Rhijn P.J., Feys B., Vanderleyden J.;
RT   "Multiple copies of nodD in Rhizobium tropici CIAT899 and BR816.";
RL   J. Bacteriol. 175:438-447(1993).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U26451; AAA26338.1; -; Genomic_DNA.
DR   PIR; B40642; B40642.
DR   AlphaFoldDB; P32008; -.
DR   SMR; P32008; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..314
FT                   /note="Nodulation protein D 2"
FT                   /id="PRO_0000105724"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   314 AA;  35440 MW;  3CB05F7230C8ACE3 CRC64;
     MRFKGLDLNL LVVLDALMTE RNLTAAARSI NLSQPAMSAA VARLRTNFRD DLFAMAGREF
     IPTPRAEGLA PAVRDALLQI QLSIVSWEPF NPAQSDRRFR IVLSDYVTLV FFEKVVARAA
     QEAPGISFDC LPLADDFEEL LRRGDIDFLI MPELFMSMHP HAALFEDKFV CVGCRTNEQL
     SEPFTFERYM SMGHVAVKFG NTRRPTIEEW YLLEHGLKRR IEVVVQGFSM IPPMLSGTER
     IGTMPLRLAQ HFAKTIPLRI VELPLPIPPL AEAVQWPALH NSDPASLWMR ELLLQEASLM
     VSPRAPVRLS APGF