NODD_AZOC5
ID NODD_AZOC5 Reviewed; 314 AA.
AC P20669; A8INU9;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 26-FEB-2008, sequence version 2.
DT 25-MAY-2022, entry version 115.
DE RecName: Full=Nodulation protein D;
GN Name=nodD; OrderedLocusNames=AZC_3792;
OS Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG
OS 6465 / NBRC 14845 / NCIMB 13405 / ORS 571).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Xanthobacteraceae; Azorhizobium.
OX NCBI_TaxID=438753;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2158977; DOI=10.1128/jb.172.5.2658-2666.1990;
RA Goethals K., van den Eede G., van Montagu M., Holsters M.;
RT "Identification and characterization of a functional nodD gene in
RT Azorhizobium caulinodans ORS571.";
RL J. Bacteriol. 172:2658-2666(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB
RC 13405 / ORS 571;
RA Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T., Kaneko T.,
RA Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B., Roe B.,
RA Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M., Oyaizu H.;
RT "Complete genome sequence of the nitrogen-fixing bacterium Azorhizobium
RT caulinodans ORS571.";
RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC encode other nodulation proteins. NodD is also a negative regulator of
CC its own expression. Binds flavonoids as inducers.
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; Z48959; CAA88827.1; -; Genomic_DNA.
DR EMBL; M60872; AAA26190.1; -; Genomic_DNA.
DR EMBL; AP009384; BAF89790.1; -; Genomic_DNA.
DR PIR; A35268; A35268.
DR AlphaFoldDB; P20669; -.
DR SMR; P20669; -.
DR STRING; 438753.AZC_3792; -.
DR EnsemblBacteria; BAF89790; BAF89790; AZC_3792.
DR KEGG; azc:AZC_3792; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_39_0_5; -.
DR OMA; CARPHVM; -.
DR Proteomes; UP000000270; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08462; PBP2_NodD; 1.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR037416; NodD_PBP2.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator; DNA-binding; Nodulation; Reference proteome; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..314
FT /note="Nodulation protein D"
FT /id="PRO_0000105699"
FT DOMAIN 6..63
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 23..42
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT CONFLICT 298
FT /note="A -> T (in Ref. 1; AAA26190/CAA88827)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 314 AA; 35551 MW; 046F300CC7D4D61A CRC64;
MRFKGLDLNL LVALNALLSE HSVTSAAKSI NLSQPAMSAA VQRLRIYFND DLFTINGRER
VFTARAESLA PAVRDILSRI QSTIIKGDLF EADRSERVFR IISSDYSTSI FIRGVISAAS
TSLPLLRFEL ISPDDNCHDL LNKSEVDALI MPEIFMSSAH PFVPLFEEKM VCVGCARNHE
DRNISSIQEY LSMRHVVAKF GRGMRPSLEE WFMAENGMRR RIDIVVQSFS MIPPVIQGTE
RIAIMPYRLV EHFSKFMPLK VFALPFPLPR FTECLQWPSI ATPDLGNRWL RAYLADHASQ
MMILDSAEYS GASI
