ID   NODD_BRASP              Reviewed;         338 AA.
AC   P04682;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Nodulation protein D;
GN   Name=nodD;
OS   Bradyrhizobium sp. (strain ANU 289).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=186901;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3960737; DOI=10.1093/nar/14.7.2905;
RA   Scott K.F.;
RT   "Conserved nodulation genes from the non-legume symbiont Bradyrhizobium sp.
RT   (Parasponia).";
RL   Nucleic Acids Res. 14:2905-2919(1986).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; X03720; CAA27346.1; -; Genomic_DNA.
DR   AlphaFoldDB; P04682; -.
DR   SMR; P04682; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..338
FT                   /note="Nodulation protein D"
FT                   /id="PRO_0000105700"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   338 AA;  38542 MW;  3046F1D68AB2C274 CRC64;
     MRFKGLDLNL LVALDALMTE RNLTAAARKI NLSQPAMSAA IARLRSYFRD ELFTMRGREL
     VLTPGAEALA GPVREALLHI QLSIISRDAF DPAQSSRRFR VILSDFMTIV FFRRIVDRIA
     QEAPAVRFEL LPFSDEPSEL LRRGEVDFLI LPELFMSSAH PKATLFDETL VCVGCPTNKQ
     LSRPLTFEKY NSMGHVTAQF GRALRPNLEE WFLLEHGLKR RIEVVVQGFS LIPPILLDTS
     RIGTMPLRLA RHFEKRMPLQ IVEPPLPLPT FTEAVQWPAF HNTDPASIWM RRILLEEASN
     MASEHREPPT PQARLDSRPR RCKNILINHS TAWPASSF