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NODD_RHILE
ID   NODD_RHILE              Reviewed;         322 AA.
AC   P16556;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Nodulation protein D;
GN   Name=nodD;
OS   Rhizobium leguminosarum.
OG   Plasmid sym pRle1001a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1001;
RX   PubMed=2979909; DOI=10.1094/mpmi-1-145;
RA   Squartini A., van Veen R.J.M., Regensberg-Tuink T., Hooyraas P.J.J.,
RA   Nuti M.P.;
RT   "Identification and characterization of the nodD gene in Rhizobium
RT   leguminosarum strain 1001.";
RL   Mol. Plant Microbe Interact. 1:145-149(1988).
CC   -!- FUNCTION: NodD regulates the expression of the nodABCFE genes which
CC       encode other nodulation proteins. NodD is also a negative regulator of
CC       its own expression. Binds flavonoids as inducers.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; J03671; AAA26299.1; -; Genomic_DNA.
DR   AlphaFoldDB; P16556; -.
DR   SMR; P16556; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08462; PBP2_NodD; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037416; NodD_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Plasmid; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..322
FT                   /note="Nodulation protein D"
FT                   /id="PRO_0000105715"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   322 AA;  37109 MW;  0BC79B3D88754AC9 CRC64;
     MRFKGLDLNL LVALDRLMTE RKLTAAARAI NLSQPAMSAA ISRWRDYFRD DLFIIQRREL
     NPTPAAEPLA PVVREALLHI QLSVIAWDPI NPAEFDRRFR IILSDFMALV FFEKIIVRLA
     REAPGVSFKL LPLDDDPEEL LRRGDVDFLI LPDLFMSGAH RKARLFEERL VCVGCSTNEQ
     LQGKLFLEQY MSMGHVAAKF GRGLKPSVEQ WLLLQQGLKR RIELVVPGFN LIPPLLSGTN
     RIATIPLRLV KHYEQTIPLR IIEHPLPLLS FTEAVQWPAL HNSDPGNIWM REIMIQEASR
     HWNPRPKVVR LKRPRSFHSR SS
 
 
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