ID   NODG_RHIML              Reviewed;         244 AA.
AC   P06235;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Nodulation protein G;
DE   AltName: Full=Host-specificity of nodulation protein C;
GN   Name=nodG; Synonyms=hsnC;
OS   Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti).
OG   Plasmid sym pRme41b.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=382;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3731273; DOI=10.1016/0092-8674(86)90654-9;
RA   Horvath B., Kondorosi E., John M., Schmidt J., Toeroek I., Gyoergypal Z.,
RA   Barabas I., Wieneke U., Schell J., Kondorosi A.;
RT   "Organization, structure and symbiotic function of Rhizobium meliloti
RT   nodulation genes determining host specificity for alfalfa.";
RL   Cell 46:335-343(1986).
CC   -!- FUNCTION: Proposed to modify Nod factor fatty acyl chain.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; M14052; AAA26288.1; -; Genomic_DNA.
DR   AlphaFoldDB; P06235; -.
DR   SMR; P06235; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   NAD; Nodulation; Oxidoreductase; Plasmid.
FT   CHAIN           1..244
FT                   /note="Nodulation protein G"
FT                   /id="PRO_0000054734"
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         11..35
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         139
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   244 AA;  26697 MW;  B5E8BDCA53D412AE CRC64;
     MFELTGRKAL VTGASGAIGG AIARVLHAQG AIVGLHGTQM KNWRHWQLSL ETGSSCSRLI
     WPIETKSRRL VRERKPILKA STSWSTNAGI TKDGLFLHMA DPDWDIVLEV NLTAMFRLTR
     EITQQMIRRR NGRIINVTSV AGAIGNPGQT NYCASKAGMI GFSKSWRRRS TRNITVNCVA
     PGFIESAMTD KLNHKQKEKI MVAIPIHRMG TGTEVASAVA YLASDHAAYV TGQTIHVNGG
     MAMI