ID   NOEK_SINFN              Reviewed;         474 AA.
AC   P55356;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Phosphomannomutase;
DE            Short=PMM;
DE            EC=5.4.2.8;
GN   Name=noeK; OrderedLocusNames=NGR_a00390; ORFNames=y4aI;
OS   Sinorhizobium fredii (strain NBRC 101917 / NGR234).
OG   Plasmid sym pNGR234a.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=394;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=9163424; DOI=10.1038/387394a0;
RA   Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A.,
RA   Perret X.;
RT   "Molecular basis of symbiosis between Rhizobium and legumes.";
RL   Nature 387:394-401(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 101917 / NGR234;
RX   PubMed=19376903; DOI=10.1128/aem.00515-09;
RA   Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A.,
RA   Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A.,
RA   Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A.,
RA   Broughton W.J., Perret X., Strittmatter A.W., Streit W.R.;
RT   "Rhizobium sp. strain NGR234 possesses a remarkable number of secretion
RT   systems.";
RL   Appl. Environ. Microbiol. 75:4035-4045(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha-D-mannose 1-phosphate = D-mannose 6-phosphate;
CC         Xref=Rhea:RHEA:11140, ChEBI:CHEBI:58409, ChEBI:CHEBI:58735;
CC         EC=5.4.2.8;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC       Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the phosphohexose mutase family. {ECO:0000305}.
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DR   EMBL; U00090; AAB91606.1; -; Genomic_DNA.
DR   RefSeq; NP_443768.1; NC_000914.2.
DR   RefSeq; WP_010875081.1; NC_000914.2.
DR   AlphaFoldDB; P55356; -.
DR   SMR; P55356; -.
DR   STRING; 394.NGR_a00390; -.
DR   EnsemblBacteria; AAB91606; AAB91606; NGR_a00390.
DR   KEGG; rhi:NGR_a00390; -.
DR   PATRIC; fig|394.7.peg.37; -.
DR   eggNOG; COG1109; Bacteria.
DR   HOGENOM; CLU_045514_1_0_5; -.
DR   OMA; VPVSCNT; -.
DR   OrthoDB; 637615at2; -.
DR   PRO; PR:P55356; -.
DR   Proteomes; UP000001054; Plasmid sym pNGR234a.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0004615; F:phosphomannomutase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR   InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR   InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR   InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR   InterPro; IPR005843; A-D-PHexomutase_C.
DR   InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR   InterPro; IPR016066; A-D-PHexomutase_CS.
DR   Pfam; PF02878; PGM_PMM_I; 1.
DR   Pfam; PF02879; PGM_PMM_II; 1.
DR   Pfam; PF02880; PGM_PMM_III; 1.
DR   Pfam; PF00408; PGM_PMM_IV; 1.
DR   SUPFAM; SSF53738; SSF53738; 3.
DR   SUPFAM; SSF55957; SSF55957; 1.
DR   PROSITE; PS00710; PGM_PMM; 1.
PE   3: Inferred from homology;
KW   Isomerase; Magnesium; Metal-binding; Nodulation; Phosphoprotein; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..474
FT                   /note="Phosphomannomutase"
FT                   /id="PRO_0000147833"
FT   ACT_SITE        101
FT                   /note="Phosphoserine intermediate"
FT                   /evidence="ECO:0000250"
FT   BINDING         101
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /note="via phosphate group"
FT                   /evidence="ECO:0000250"
FT   BINDING         242
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         244
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         246
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   474 AA;  49671 MW;  6965310CEA96A22B CRC64;
     MGPKFGTSGL RGLATELVGS VSALYATAFS RMLLDRGRVA PGATVLVGRD FRDSSSEIAA
     ICMAALARAG MVPVDCGGLP TPALALYGRK LGAASLMITG SHIPADRNGI KFYLPDGEIN
     KADEQAITAL AEQLSADADA TRVECGRGAD HSSEATDFYI QRYETLLPKS GLKGLKIGLY
     QHSSVARDIL TTILEGHGAN VVPVGRSEVF IPVDTEAISA ATCKMLAAWA KEFAFDAIVS
     SDADADRPLL TDETGTPLRG DLLGLICARL LEAKLIATPI TSNSGIEAAS GVEVVRTRVG
     SPYVIAAMTE AVARGKQRVM GFEANGGVML GSNFSFGGAS LPALPTRDCV LPIIAALHMA
     VEAKTPLSGI VAMHRLPVAL SGRIENYPFD RSDALVAFLK ASKANVSHLF SRIGRVAGTD
     DVDGLRLTFE GGRILHIRPS GNAPELRCYV EADDPDAAEH LLAQGLAVLN SSMV