ID   NOL10_XENLA             Reviewed;         689 AA.
AC   Q7T0Q5; Q7ZYE7;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Nucleolar protein 10;
GN   Name=nol10;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH43816.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
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DR   EMBL; BC043816; AAH43816.1; ALT_SEQ; mRNA.
DR   EMBL; BC056086; AAH56086.1; -; mRNA.
DR   RefSeq; NP_001082737.1; NM_001089268.1.
DR   AlphaFoldDB; Q7T0Q5; -.
DR   SMR; Q7T0Q5; -.
DR   DNASU; 398690; -.
DR   GeneID; 398690; -.
DR   KEGG; xla:398690; -.
DR   CTD; 398690; -.
DR   Xenbase; XB-GENE-5800096; nol10.L.
DR   OMA; GEWVMST; -.
DR   OrthoDB; 1099332at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 398690; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR040382; NOL10/Enp2.
DR   InterPro; IPR012580; NUC153.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR14927; PTHR14927; 1.
DR   Pfam; PF08159; NUC153; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..689
FT                   /note="Nucleolar protein 10"
FT                   /id="PRO_0000051105"
FT   REPEAT          50..90
FT                   /note="WD 1"
FT   REPEAT          174..213
FT                   /note="WD 2"
FT   REPEAT          228..266
FT                   /note="WD 3"
FT   REPEAT          270..308
FT                   /note="WD 4"
FT   REPEAT          310..349
FT                   /note="WD 5"
FT   REGION          529..592
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          646..689
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          422..476
FT                   /evidence="ECO:0000255"
FT   COILED          511..590
FT                   /evidence="ECO:0000255"
FT   COILED          647..679
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        544..586
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        648..673
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        292
FT                   /note="S -> F (in Ref. 1; AAH43816)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   689 AA;  80449 MW;  28DE28D7800DC556 CRC64;
     MQVSNVNDVK IYNLSCGKSL PEWLSDRKKR ALQKKDVDVR RRIELIQDFE MPTVSTNIKV
     SRDGQYIMAA GTYKPRIRCY DTYQLSLKFE RCLDSEVIKF DILSEDYSKI VFLQSDRYVE
     LHSQHGRYYR LRIPKFGRDF AYHYPSCDLY FVGASSEVYR LNLEQGRYLN SLQTEASQIN
     VCDINPTHHL FAAGTTEGRV ECWDPRTRSR VGLLDCALSS VTADMEVEGL PSVSALKFNG
     PLHMAVGTST GQVLLYDLRS NRPVIVKDHQ YGLPIKSIQF HSALDLVISA DSRIIKMWNK
     DNGKIFTSIE PEADVNDVCL YPNSGMLFTA NEAPKMNVYY IPALGPAPRW CSFLDNLTEE
     LEENPENTVY DDYKFVTRKE LDELGLSHLI GSPMLRAYMH GFFMDIRLYH KVKAMVNPFA
     YEEYKKEKIR QKIEETRAQR VQIKKLPKVN KELALKLYED EEEEKQLSKK KKKQKKMPNI
     LTDDRFKVMF ENPDFQVDQE SEEYRLLNPL VSKISEKRKK KLKILEKLEA EGEEEEEEPE
     GKPSDAESSE TSDDEKGWVE EVRKQRKLLR QEEKERRQER VREDQQTALK PQFYEIKAGE
     EFRSFQDAAK KQKLMRKTLE DRIKVEEKLG TLNVADTAVG SKQLTFTLKK SEQHRKRQEA
     EKQHQEERKK LRRSAGHLKS KQAKGRPFY