NOL10_XENTR
ID NOL10_XENTR Reviewed; 686 AA.
AC Q6NVM6;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Nucleolar protein 10;
GN Name=nol10;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family. {ECO:0000305}.
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DR EMBL; BC067979; AAH67979.1; -; mRNA.
DR RefSeq; NP_998842.1; NM_213677.1.
DR AlphaFoldDB; Q6NVM6; -.
DR SMR; Q6NVM6; -.
DR STRING; 8364.ENSXETP00000007599; -.
DR DNASU; 407887; -.
DR GeneID; 407887; -.
DR KEGG; xtr:407887; -.
DR CTD; 79954; -.
DR Xenbase; XB-GENE-5799993; nol10.
DR eggNOG; KOG2321; Eukaryota.
DR InParanoid; Q6NVM6; -.
DR OrthoDB; 1099332at2759; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 2.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR14927; PTHR14927; 1.
DR Pfam; PF08159; NUC153; 1.
DR SMART; SM00320; WD40; 4.
DR SUPFAM; SSF50978; SSF50978; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Nucleus; Reference proteome; Repeat; WD repeat.
FT CHAIN 1..686
FT /note="Nucleolar protein 10"
FT /id="PRO_0000051106"
FT REPEAT 50..90
FT /note="WD 1"
FT REPEAT 174..213
FT /note="WD 2"
FT REPEAT 228..266
FT /note="WD 3"
FT REPEAT 270..308
FT /note="WD 4"
FT REPEAT 310..349
FT /note="WD 5"
FT REGION 526..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 420..470
FT /evidence="ECO:0000255"
FT COILED 555..587
FT /evidence="ECO:0000255"
FT COILED 639..676
FT /evidence="ECO:0000255"
FT COMPBIAS 541..583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..686
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 686 AA; 79884 MW; F0FABF5A4927866E CRC64;
MQVSNVNDVK IYNLSCGKSL PEWLSDRKKR ALQKKDVDVR RRIELIQDFE MPTVSTNIKV
SRDGQYIMAA GTYKPRVRCY DTYQLSLKFE RCLDAEVVKF DILSEDYSKI VFLQSDRYVE
LHSQHGRYYR LRIPKFGRDF AYHYPSCDLY FVGASSEVYR LNLEQGRYLN SLQTDASQIN
VCDINPAHHL FAAGTTEGKV ECWDPRTRNR VGLLDCALSS VTADMEVEGL PSVSALKFHG
PLHMAVGTST GQVVLYDLRS NRPLIAKDHQ YGLPIKSIQF HSALDLVISA DSRIIKMWNK
DNGKIFTSIE PEADVNDVCL YPNSGMLFTA NEAPKMNVYY IPALGPAPRW CSFLDNLTEE
LEENPESTVY DDYKFVTRKE LDELGLSHLI GSPLLRAYMH GFFMDIRLYH KVKAMVNPFA
YEEYKKEKIR QKIEEARAQR VQIKKLPKVN KELALKLYEE EEELSQKKKK QKKMPNILSD
DRFKVMFENP DFQVDQESEE YRLLNPLVSK ISEKRKKKLK ILEKLDAEDG EEEEEPEGKP
SDAESSESSD DEKGWVEEVR KQRKLLRQEE KQRRQERVRE DQQTALKPQF YEIKAGEEFR
SFQDAAKKQK LMRKTLEDRV KVEEKLGTLN VSDTAVGSKQ LTFTLKKFEQ HRKRQEAEKQ
HQEERKKLRR SAGHLKSKPA RGRPFH