ID   NOL11_DANRE             Reviewed;         708 AA.
AC   Q4V9P9;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Nucleolar protein 11-like;
GN   Name=nol11; ORFNames=wu:fb30e03, zgc:109901;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ribosome biogenesis factor. May be required for both optimal
CC       rDNA transcription and pre-rRNA processing (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; BC096784; AAH96784.1; -; mRNA.
DR   RefSeq; NP_001025234.1; NM_001030063.1.
DR   AlphaFoldDB; Q4V9P9; -.
DR   SMR; Q4V9P9; -.
DR   STRING; 7955.ENSDARP00000032159; -.
DR   PaxDb; Q4V9P9; -.
DR   PRIDE; Q4V9P9; -.
DR   GeneID; 321700; -.
DR   KEGG; dre:321700; -.
DR   CTD; 25926; -.
DR   ZFIN; ZDB-GENE-030131-419; nol11.
DR   eggNOG; ENOG502SB74; Eukaryota.
DR   InParanoid; Q4V9P9; -.
DR   OrthoDB; 570601at2759; -.
DR   PhylomeDB; Q4V9P9; -.
DR   Reactome; R-DRE-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   PRO; PR:Q4V9P9; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; ISS:UniProtKB.
DR   GO; GO:1901838; P:positive regulation of transcription of nucleolar large rRNA by RNA polymerase I; ISS:UniProtKB.
DR   InterPro; IPR042859; NOL11.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR15633; PTHR15633; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
PE   2: Evidence at transcript level;
KW   Activator; Nucleus; Reference proteome; rRNA processing; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..708
FT                   /note="Nucleolar protein 11-like"
FT                   /id="PRO_0000096929"
SQ   SEQUENCE   708 AA;  78589 MW;  30F2DA91646BB0F5 CRC64;
     MATLYEEYTL CGVGPDKNSS SSGILGIELG KDVDHIIVTN SSRAVTVYKV SDQKPTGSWT
     VKQGQLITCP AVYNTKSQEY VVVTDNKVIR VWKEDDVNME KAFKATVSSD VLRVIAASDS
     EPVVLFSCGA VMFLDSLLAS PQQTIEGVLT EEEFIRWSTV VGAEHQLVLL FCTEKRGEHY
     LYAQRFNPNT VVKHRFETEP GPFAPISFSA TCRGSNIHLQ YLYMSGRIYE SVLPLRSSVS
     EAEGVQALPR SLCLSLPLGE QELTSGAAIV LDEAHVAIVG FPHPSAGAGK DYLCIWNKHF
     QTLQACKELA GTIYSQIWCY SGKLYIPHGK ILSVISFECQ KSSLAAAMGK LKQTNQSESK
     SHTPLSSWTA LPHNDSINAA KVKSRMSTRN ASNVKSPLTV DQLIDHIKTA VVEDVQSAVG
     EFIHQTPQTD LQLAAGKVTM VLVSRSQTDD SFYPQRAFLQ LLDTRYLCYS VCPELLSLAM
     AKRDFQLCQI AFQLFPDIPE AVTCAYLKTI LSTPDSEMET LTLDTESLII MKEMSPAQSQ
     MEEGEQQNEN GVSSSKQQRD FLSMDMKCPV GLHKGVLLND VLQTAYSDKP LLQHLKDLTV
     LQVMVFLQYL HFLYLKYSQD VHKQIRALRI PSISQVIDWA SLILDAHFTV LAVAPEAKSL
     VSDLHKFTRS QVKLYAELGK IEGSLQSLKK PKSTEHTGVY SIEVIELF