ID   NOL11_XENLA             Reviewed;         720 AA.
AC   Q6INI5; Q52L03;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   30-AUG-2005, sequence version 2.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Nucleolar protein 11;
GN   Name=nol11;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Eye;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ribosome biogenesis factor. May be required for both optimal
CC       rDNA transcription and pre-rRNA processing (By similarity).
CC       {ECO:0000250|UniProtKB:Q9H8H0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9H8H0}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH72295.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAH94122.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC072295; AAH72295.1; ALT_INIT; mRNA.
DR   EMBL; BC094122; AAH94122.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q6INI5; -.
DR   SMR; Q6INI5; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; ISS:UniProtKB.
DR   GO; GO:1901838; P:positive regulation of transcription of nucleolar large rRNA by RNA polymerase I; ISS:UniProtKB.
DR   InterPro; IPR042859; NOL11.
DR   PANTHER; PTHR15633; PTHR15633; 1.
PE   2: Evidence at transcript level;
KW   Activator; Nucleus; Reference proteome; Ribosome biogenesis;
KW   rRNA processing; Transcription; Transcription regulation.
FT   CHAIN           1..720
FT                   /note="Nucleolar protein 11"
FT                   /id="PRO_0000096934"
FT   REGION          365..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   720 AA;  80095 MW;  85CA1DC89BDEAADC CRC64;
     MAALSEHFTL CGLLTGTDDG KSEILGVEPA GEPDRVLVTD SVQAVTLYKV SDQKPQGAWA
     VKQGQSITCP AVLNPESGEF IVVHDDKVLR IWKEDNVNLD IAFKATLSAD VCRIHTLPNT
     DPLVLFKGGA VHFLDSLLTD PQQKIGTVLS DGERIVWSEI FADDGQPLIV YLTQQFSNYF
     VYIHKFSPVC VCKYHLKPNT EDSTILDCSG SVKSKIFTLL TLYSSGQVCQ TPFPVSLINK
     ETERVVSASP LLQLSGPIEV GALNFLDESH VAVLISSSSE QKECLSIWNT TFQTLQAARN
     FQQRTSAQLW CYDNKLFVPH GKTLVVVPYV CEASCLASVL GKSRNIQTSV LENVPFVNWD
     KLVGKDPETK PSNAGAQKKT RERKTNANAG NGTESILYPF DVQNISQTQT EAFVQQLLLG
     KEDTDFQITV GKITQGLVKR CMADPKFYPQ SSFVQLVQTN TLSYSLCPDL LSLFLEKRDV
     PLLQLCLHSF PDVPEVILCS CLKAFLSISE KLVNAAQINT ELASLYIDVG DKDKEHKYTE
     HPEEPSVLQN GFSPTALEED SCDELIAESL PQTTQKATCP ISIKRAVLVN SILISPYNES
     FLLPHLKDMS GDQVMFFLRY LLYLYLKFNE NITINHPGKQ MPTVSQIVDW MSMLLDAHFA
     TVVMLSDAKA LLNKIQKTVK SQLKFYSEMN KIEGCLAELK ELKCPARVSA RYSIEVLQLY