ID   NOL12_DANRE             Reviewed;         228 AA.
AC   Q7ZWE7;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Nucleolar protein 12;
GN   Name=nol12; ORFNames=zgc:56457;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=SJD;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May bind to rRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP17 family. {ECO:0000305}.
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DR   EMBL; BC049449; AAH49449.1; -; mRNA.
DR   RefSeq; NP_956584.1; NM_200290.1.
DR   AlphaFoldDB; Q7ZWE7; -.
DR   STRING; 7955.ENSDARP00000123934; -.
DR   PaxDb; Q7ZWE7; -.
DR   Ensembl; ENSDART00000148524; ENSDARP00000123934; ENSDARG00000038027.
DR   GeneID; 393260; -.
DR   KEGG; dre:393260; -.
DR   CTD; 79159; -.
DR   ZFIN; ZDB-GENE-040426-1035; nol12.
DR   eggNOG; KOG4709; Eukaryota.
DR   GeneTree; ENSGT00390000015973; -.
DR   HOGENOM; CLU_111183_0_0_1; -.
DR   InParanoid; Q7ZWE7; -.
DR   OMA; HKEYVKM; -.
DR   OrthoDB; 1635966at2759; -.
DR   PhylomeDB; Q7ZWE7; -.
DR   TreeFam; TF323855; -.
DR   PRO; PR:Q7ZWE7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000038027; Expressed in tail and 22 other tissues.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR019186; Nucleolar_protein_12.
DR   PANTHER; PTHR14577; PTHR14577; 1.
DR   Pfam; PF09805; Nop25; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; RNA-binding; rRNA-binding.
FT   CHAIN           1..228
FT                   /note="Nucleolar protein 12"
FT                   /id="PRO_0000271211"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..228
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          40..103
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        126..146
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..169
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..184
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   228 AA;  26515 MW;  D5685A5522C8544A CRC64;
     MGKSDRLQQG SKGKGGGKRK HGKCVLMFDD KDRQDFLTGF HKRKLERRRA ALEEMKSKLK
     EEQKRLREER HKEYLKMLQE RRQALDEADE LEEAITATTE CVQYDHPNHT VTVTTISDLD
     LSADRLLEPA QRDGGDGEER ERTEALPKQA GNPLLSKKIQ SLTASLNSLV KQKKRRKQKR
     RQEAKQRSHQ SDRKSSSSAF VHNNKQKQGK STKRQRRRQT GRNERSQD