ID   NOL12_PONAB             Reviewed;         213 AA.
AC   Q5RD68;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Nucleolar protein 12;
GN   Name=NOL12;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May bind to 28S rRNA. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with KIAA1191. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP17 family. {ECO:0000305}.
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DR   EMBL; CR858049; CAH90289.1; -; mRNA.
DR   RefSeq; NP_001125131.1; NM_001131659.1.
DR   AlphaFoldDB; Q5RD68; -.
DR   SMR; Q5RD68; -.
DR   PRIDE; Q5RD68; -.
DR   GeneID; 100172016; -.
DR   KEGG; pon:100172016; -.
DR   CTD; 79159; -.
DR   InParanoid; Q5RD68; -.
DR   OrthoDB; 1635966at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR019186; Nucleolar_protein_12.
DR   PANTHER; PTHR14577; PTHR14577; 1.
DR   Pfam; PF09805; Nop25; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; RNA-binding; rRNA-binding.
FT   CHAIN           1..213
FT                   /note="Nucleolar protein 12"
FT                   /id="PRO_0000271209"
FT   REGION          109..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          33..96
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        136..150
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..185
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        194..213
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   213 AA;  24655 MW;  45550B43DE64A0D2 CRC64;
     MGRNKKKKRD GDDRRPRLVL SFDEEKRREY LTGFHKRKVE RKKAAIEEIK QRLKEEQRKL
     REERHQEYLK MLAEREEALE EADELDRLVT AKTESVQYDH PNHTVTATTI SDLDLSGARL
     LGLTPPEGGA GDESEEEASS TEKPTKALPR KSRDPLLSQR ISSLTASLHA HSRKKVKRKH
     PRQAQDSKKP PRATRTSKAQ RRRLTGKAQH SRE