NOL12_XENLA
ID NOL12_XENLA Reviewed; 220 AA.
AC Q0IH29;
DT 09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Nucleolar protein 12;
GN Name=nol12;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Ovary;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May bind to rRNA. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the RRP17 family. {ECO:0000305}.
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DR EMBL; BC123345; AAI23346.1; -; mRNA.
DR RefSeq; NP_001090400.1; NM_001096931.1.
DR AlphaFoldDB; Q0IH29; -.
DR SMR; Q0IH29; -.
DR DNASU; 779312; -.
DR GeneID; 779312; -.
DR KEGG; xla:779312; -.
DR CTD; 779312; -.
DR Xenbase; XB-GENE-1188371; nol12.S.
DR OrthoDB; 1635966at2759; -.
DR Proteomes; UP000186698; Chromosome 4S.
DR Bgee; 779312; Expressed in blastula and 19 other tissues.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR019186; Nucleolar_protein_12.
DR PANTHER; PTHR14577; PTHR14577; 1.
DR Pfam; PF09805; Nop25; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Nucleus; Reference proteome; RNA-binding; rRNA-binding.
FT CHAIN 1..220
FT /note="Nucleolar protein 12"
FT /id="PRO_0000271212"
FT REGION 109..220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 31..86
FT /evidence="ECO:0000255"
FT COMPBIAS 125..152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..220
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 25788 MW; 438A238C5127E26E CRC64;
MGKKKQKKGQ GSRLEVIFDE EKRREYLTGF HKRKMQRRKT AVEEIKRKIK EEQKKMKEER
HKEYMKMLKE REEALCELEE NDELEEMVTS KTESVRYDHP NHTVTVTTIS DLDLSGIRVP
PLGNAEQKQE EEKVEEENEK GADEEKPKTS VSLPKKSGDP FLSKKICSLT ASLHARSQRK
SGKRPSRTNE NKKQTSSKMS GRTSKTQRRK QTGKTRRRRN