ID   NOL12_XENTR             Reviewed;         216 AA.
AC   Q640V3;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Nucleolar protein 12;
GN   Name=nol12; ORFNames=TNeu122o09.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=F6;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May bind to rRNA. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRP17 family. {ECO:0000305}.
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DR   EMBL; CR942728; CAJ82350.1; -; mRNA.
DR   EMBL; BC082486; AAH82486.1; -; mRNA.
DR   RefSeq; NP_001008168.1; NM_001008167.1.
DR   RefSeq; XP_012816419.1; XM_012960965.2.
DR   RefSeq; XP_012816420.1; XM_012960966.2.
DR   RefSeq; XP_012816421.1; XM_012960967.1.
DR   AlphaFoldDB; Q640V3; -.
DR   SMR; Q640V3; -.
DR   Ensembl; ENSXETT00000034873; ENSXETP00000034873; ENSXETG00000015984.
DR   GeneID; 493530; -.
DR   KEGG; xtr:493530; -.
DR   CTD; 79159; -.
DR   Xenbase; XB-GENE-1011565; nol12.
DR   InParanoid; Q640V3; -.
DR   OrthoDB; 1635966at2759; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000015984; Expressed in ovary and 12 other tissues.
DR   ExpressionAtlas; Q640V3; differential.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR019186; Nucleolar_protein_12.
DR   PANTHER; PTHR14577; PTHR14577; 1.
DR   Pfam; PF09805; Nop25; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; RNA-binding; rRNA-binding.
FT   CHAIN           1..216
FT                   /note="Nucleolar protein 12"
FT                   /id="PRO_0000271213"
FT   REGION          120..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          167..216
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          30..83
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        199..216
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   216 AA;  24903 MW;  3987F65EE8875EF2 CRC64;
     MGKKKQKKGS TSCRELTFDE EKRREYLTGF HKRKMQRRKA AVEEIKRKIK EEQKKMREER
     HKEYMKMLKE REEALCELEE TDELEGLVTS KCESVQYDHP NHTVTVTTIS DLDLSGIGLL
     PLGKAQQEEE EENEKDADEE QPKSSVSLPK KAGDPFLSKK ICSLTASLHA RSQRKAGKRP
     SRTNDKKKQT SGKQVSGRTS KAQRRKQTGK IGRNRD