ID   NOL6_DROMO              Reviewed;        1187 AA.
AC   B4K5S6;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE   AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN   Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GI24653;
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230;
RN   [1] {ECO:0000312|EMBL:EDW15138.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22 {ECO:0000312|EMBL:EDW15138.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8R5K4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR   EMBL; CH933806; EDW15138.1; -; Genomic_DNA.
DR   RefSeq; XP_001999677.1; XM_001999641.2.
DR   AlphaFoldDB; B4K5S6; -.
DR   SMR; B4K5S6; -.
DR   STRING; 7230.FBpp0173870; -.
DR   EnsemblMetazoa; FBtr0175378; FBpp0173870; FBgn0147375.
DR   GeneID; 6573611; -.
DR   KEGG; dmo:Dmoj_GI24653; -.
DR   eggNOG; KOG2054; Eukaryota.
DR   HOGENOM; CLU_003502_0_1_1; -.
DR   InParanoid; B4K5S6; -.
DR   OMA; NPHGGKE; -.
DR   OrthoDB; 176625at2759; -.
DR   PhylomeDB; B4K5S6; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1187
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000383625"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1134..1187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        34..64
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1134..1160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1187 AA;  134441 MW;  185726DC7FF8515D CRC64;
     MGRIKENQSK KKTLLRDSKA YSDQAAAAVT SSDDGFDEPK EITAPKRKLP CGNSDAKKKK
     FKHPEANVKP PTLEEIKEIR DTRNLFHSNL FKLQVKEMLE ELQLKPKYSN YIENWLETFT
     TAVHEFQDGL LDNCQLEVPL HLHKKLFNFQ FLTPTAEPKL IGAAAIGTLL GPKLVVDVAL
     EMPEKCFQKE DYRNLIFDQK RALYLATVAS KLKELPACAA DHFAYNYHAN NPLKPVLELT
     PTGKIGKHLS LRLYITAPKA IFKLSRFVPW NNNVRPSFFG DKWDESETLP STQHYNANVL
     FDLTLAENQK LLLSTFSGHR NFQEGLLLLK VWLRQRQLDV GFSGFSAHIL AAYIVYLKQN
     RLLHQSSSSY QVARTVWNQL ANSDWTQGIT LCPQQPHQLS TLAGYYDVCF MDVTGYYNIC
     ANLPLSVYKA VCAEAKLAVE LLNDVRVNSF SQIFMQASPL YTRMDNILKI TNPATVDQLL
     ELHVQPQVKY DYANYAHPQL LKLLTDLLQK GLGKRVHAIL PLETASKSWT VDTKAPIIGR
     SLTLGLILDP EHAFEVLDKG PATNEDAEGA AEFRKFWGEK SNLRRFQDGS ITEAVVWAAV
     TDAPSKKRLI VRQIVLHLLE QHLQLEQSDV HYIAGELDII YSLTSSFKVA KLQTKLKLEQ
     ETDAEAVTPL VIHCYDALAR QLHTLGDLPL DIVSISGISP VFRYCEPQPL LPQARLVADR
     MHAGHVLRVI IQLGPSGKWP NELGALRSLK TAFLIQIGKQ LKEQQHLHTQ LCKEGLLVLK
     QGYCFLLELA HTKEVALLKQ QQTERGVTAY VDNAASREIE RRHYILPRVS GALHALHQSH
     STFGPTVLIA KRWLATQMID DGLWPSIATE LLVAHLFQQR QMPHTTVAPQ TGFIRFLQLL
     AHSDWASELF LLNFNNSWTE QQITDLEHSY RSERDSYPAL CLATAYDQQH AGRLWTTDDC
     PSKPVLGRVT LLARHALQLI ESSLLSPSLG FVRPAQLFIA SGEGYDLVIE LKPDLLPNTL
     CYDLGSPFLP FSQRNFRLPL AGIDQLAKIV QQLRSAYSEY AAFFYNPHGG KELAIVWRPA
     SEFAPKPFKV NELQACTPCS VGKVQVVRDT LVEDFKLLLK DFYLRICTPE QLKREQRSHN
     KPKRYFDDQS EPDVDKPQKK KKKKGTVTKP TDLKKRLKKS KSLSALC