NOL6_DROPE
ID NOL6_DROPE Reviewed; 1212 AA.
AC B4GFN6;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 50.
DE RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GL22251;
OS Drosophila persimilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7234;
RN [1] {ECO:0000312|EMBL:EDW34421.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSH-3 / Tucson 14011-0111.49;
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q8R5K4}.
CC -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR EMBL; CH479182; EDW34421.1; -; Genomic_DNA.
DR RefSeq; XP_002017321.1; XM_002017285.1.
DR AlphaFoldDB; B4GFN6; -.
DR SMR; B4GFN6; -.
DR STRING; 7234.FBpp0186358; -.
DR PRIDE; B4GFN6; -.
DR EnsemblMetazoa; FBtr0187866; FBpp0186358; FBgn0159843.
DR GeneID; 6591684; -.
DR KEGG; dpe:6591684; -.
DR eggNOG; KOG2054; Eukaryota.
DR HOGENOM; CLU_003502_0_1_1; -.
DR OMA; NPHGGKE; -.
DR PhylomeDB; B4GFN6; -.
DR Proteomes; UP000008744; Unassembled WGS sequence.
DR GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR005554; NOL6/Upt22.
DR InterPro; IPR035082; Nrap_D1.
DR InterPro; IPR035367; Nrap_D2.
DR InterPro; IPR035368; Nrap_D3.
DR InterPro; IPR035369; Nrap_D4.
DR InterPro; IPR035370; Nrap_D5.
DR InterPro; IPR035371; Nrap_D6.
DR PANTHER; PTHR17972; PTHR17972; 1.
DR Pfam; PF03813; Nrap; 1.
DR Pfam; PF17403; Nrap_D2; 1.
DR Pfam; PF17404; Nrap_D3; 1.
DR Pfam; PF17405; Nrap_D4; 1.
DR Pfam; PF17406; Nrap_D5; 1.
DR Pfam; PF17407; Nrap_D6; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..1212
FT /note="Nucleolar protein 6"
FT /id="PRO_0000383626"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1212 AA; 137690 MW; 52D3B9841C6B32A7 CRC64;
MGKIKKIQRK GPPATKRPPK AARTESTDSA LGLDAHSDLE KPATSSDDGF EEPTPKPKPS
KKTTTLPEPV SIIAQKKNKF RTDDAKNVKP PTLEEMKELR DTRNLFHSNL FKLQVKEMLE
ELQLKTKYTE YIDNWMESFT VFTQRLKDGL VEKSQLEVPL NVDKKISGFI FSKPTKEPQL
IGAASTGTLL GPKIVVDVAL EMPKDCLHKD DYLNLIYDQK RALYLTYVTN QMRSDPAYSQ
DKFAFNYHGN NPLKPVLELT PAAKHVSKHL QLRLFITAPQ STFKPGRFVP WNNNIRPTYY
NDEWDEEEAL PSTQHYNASV LFDLTLAQNQ ALLDKAFKGR RNFQDGLLLL KVWLRQRELD
RGFTGFGSHI LASFIVYLNQ QRILHQSSSS YQVARTVWNQ LANTDWTNGI TLAPASGQTE
QLSTIAGYYD VCFMDVSGQL NLCANVPLGV YQRVRAEAKL AVDLLNDMKL NSFPYIFMQK
CPLYTRVDNI LKITNYSSIQ QMLVLHSKPQ MKYDFASYGY PQLLQILTEL LQKGLKQRVQ
AILPIETVSS AWPVESKAPI IGQAIQLGLI LDPEHAYEVL DKGPSSNDDP EGSAEFRKFW
GEKSNLRRFQ DGSITEAVVW GTTKDAPSKK RLIVRQIVMH LLEHHLQLDS KDIQYIAAEL
DLVYQLSPWF KVSKVKTKLE LQQDTDAEAL SPNVIRCYDD LARQLHALDD LPLEIVSISS
ISPVSRYCEP MPVLPQARMM ADHIHASHIQ RVIIQLGQSG KWPNELSALR ALKTAFLIEI
GEKLKAQCRL NWSITSEGLL VLKRGFCFLL ELAHNKELAL LKQEVTERGV TKYVDNPESR
ALEQRHYILP KVSGALHSLH QSHSAYGPTV LIAKRWLATQ LLDDGIWPPM ATELLVAHLY
QQRNAPQAIA APQTGFMRLL HLLAHSDWNG ELFLLNFNSS WQEQQIGDLE HSFRSDRQSY
PPLALATSYD QQHAGRLWTT GESPSLRILS HVSRLARHAL EMIETSLQSK DLRFVRPAQL
FRGSSEGYDL VIQLKSDLVP NALSYDLGSP FVSFDQPNYL LPRAGKDPLA AIVHQLRSAY
SDYAAFFYNP HGGKELAIMW RPPAVFAPKA FKVTELQACT LCDKGKVQVV RETLVEDFKV
LLKDFYLRIS TPEELKREQR EHQNPKRYFN AKPQDNESCS KSKKRKLAKA AKVQAPLKRK
SLIKSRPLKS LS