NOL6_DROPS
ID NOL6_DROPS Reviewed; 1212 AA.
AC Q295U7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 2.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GA11810;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1] {ECO:0000312|EMBL:EAL28611.2}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q8R5K4}.
CC -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR EMBL; CM000070; EAL28611.2; -; Genomic_DNA.
DR RefSeq; XP_001359465.2; XM_001359428.3.
DR AlphaFoldDB; Q295U7; -.
DR SMR; Q295U7; -.
DR STRING; 7237.FBpp0284514; -.
DR EnsemblMetazoa; FBtr0286076; FBpp0284514; FBgn0071859.
DR GeneID; 4802570; -.
DR KEGG; dpo:Dpse_GA11810; -.
DR eggNOG; KOG2054; Eukaryota.
DR HOGENOM; CLU_003502_0_1_1; -.
DR InParanoid; Q295U7; -.
DR OMA; NPHGGKE; -.
DR Proteomes; UP000001819; Chromosome 2.
DR Bgee; FBgn0071859; Expressed in female reproductive system and 3 other tissues.
DR GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR005554; NOL6/Upt22.
DR InterPro; IPR035082; Nrap_D1.
DR InterPro; IPR035367; Nrap_D2.
DR InterPro; IPR035368; Nrap_D3.
DR InterPro; IPR035369; Nrap_D4.
DR InterPro; IPR035370; Nrap_D5.
DR InterPro; IPR035371; Nrap_D6.
DR PANTHER; PTHR17972; PTHR17972; 1.
DR Pfam; PF03813; Nrap; 1.
DR Pfam; PF17403; Nrap_D2; 1.
DR Pfam; PF17404; Nrap_D3; 1.
DR Pfam; PF17405; Nrap_D4; 1.
DR Pfam; PF17406; Nrap_D5; 1.
DR Pfam; PF17407; Nrap_D6; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..1212
FT /note="Nucleolar protein 6"
FT /id="PRO_0000383627"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1156..1212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1212 AA; 137628 MW; 8D391865C8071A2A CRC64;
MGKIKKILRK GPPATKRPPK AARTESADSA LGLDAHSDLE KPATSSDDGF EEPTPKPKPS
KKTTTLPGPV SIIAQKKNKF RTDDAKNVKP PTLEEMKELR DTRNLFHSNL FKLQVKEMLE
ELQLKTKYTE YIDNWMESFT VFTQRLKDGL VEKSQLEVPL NVDKKISGFI FSKPTKEPQL
IGAASTGTLL GPKIVVDVAL EMPKDCLHKD DYLNLIYDQK RALYLTYVTN QMRSDPAYSQ
DKFAFNYHGN NPLKPVLELT PAAKQVSKHL QLRLFITAPQ STFKPSRFVP WNNNIRPTYY
NDEWDEEEAL PSTQHYNASV LFDLTLAQNQ ALLDKAFKGR RNFQDGLLLL KVWLRQRELD
RGFTGFGSHI LASFIVYLNQ QRILHQSSSS YQVARTVWNQ LANTDWTNGI TLAPASGQTE
QLSTMAGYYD VCFMDVSGQL NLCANVPLGV YQRVRAEAKL AVDLLNDMKL NSFPYIFMQK
CPLYTRVDNI LKITNYSSIQ QMLVLHSKPQ MKYDFASYGY PQLLQILTEL LQKGLKQRVQ
AILPIETVSS AWPVESKAPI IGQAIQLGLI LDPEHAYEVL DKGPSSNDDP EGSAEFRKFW
GEKSNLRRFQ DGSITEAVVW GTTKDAPSKK RLIVRQIVMH LLEHHLQLDS KDIQYIAAEL
DLVYQLSPWF KVSKVKTKLE LQQDTDAEAL SPNVIRCYDD LARQLHALDD LPLEIVSISS
ISPVSRYCEP MPVLPQARMM ADHIHASHIQ RVIIQLGQSG KWPNELSALR ALKTAFLIEI
GEKLKAQCRL NWSITSEGLL VLKRGFCFLL ELAHNKELAL LKQEVTERGV TKYVDNPESR
ALEQRHYILP KVSGALHSLH QSHSAYGPTV LIAKRWLATQ LLDDGIWPPM ATELLVAHLY
QQRNAPQAIA APQTGFIRFL HLLAHSDWNG ELFLLNFNSS WQEQQIGDLE HSFRSDRQSY
PPLALATSYD QQHAGRLWTT GESPSLRILS HVSRLARHAL EMIETSLQSK DLRFVRPAQL
FRGSSEGYDL VIQLKSDLVP NALSYDLGSP FVSFDQPNYL LPRAGKDPLA AIVHQLRSAY
SDYAAFFYNP HGGKELAIMW RPPAVFAPKA FKVTELQACT LCDKGKVQVV RETLVEDFKV
LLKDFYLRIS TPEELKREQR EHQNPKRYFN AKPQDNESCS KSKKRKLAKA AKVQAPLKRK
SLIKSRPLKS LS