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NOL6_DROPS
ID   NOL6_DROPS              Reviewed;        1212 AA.
AC   Q295U7;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 2.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE   AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN   Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GA11810;
OS   Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=46245;
RN   [1] {ECO:0000312|EMBL:EAL28611.2}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MV2-25 / Tucson 14011-0121.94;
RX   PubMed=15632085; DOI=10.1101/gr.3059305;
RA   Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA   Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA   Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA   Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA   Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA   Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA   Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA   Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA   Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA   Weinstock G.M., Gibbs R.A.;
RT   "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT   gene, and cis-element evolution.";
RL   Genome Res. 15:1-18(2005).
CC   -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8R5K4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR   EMBL; CM000070; EAL28611.2; -; Genomic_DNA.
DR   RefSeq; XP_001359465.2; XM_001359428.3.
DR   AlphaFoldDB; Q295U7; -.
DR   SMR; Q295U7; -.
DR   STRING; 7237.FBpp0284514; -.
DR   EnsemblMetazoa; FBtr0286076; FBpp0284514; FBgn0071859.
DR   GeneID; 4802570; -.
DR   KEGG; dpo:Dpse_GA11810; -.
DR   eggNOG; KOG2054; Eukaryota.
DR   HOGENOM; CLU_003502_0_1_1; -.
DR   InParanoid; Q295U7; -.
DR   OMA; NPHGGKE; -.
DR   Proteomes; UP000001819; Chromosome 2.
DR   Bgee; FBgn0071859; Expressed in female reproductive system and 3 other tissues.
DR   GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1212
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000383627"
FT   REGION          1..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1156..1212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..58
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1212 AA;  137628 MW;  8D391865C8071A2A CRC64;
     MGKIKKILRK GPPATKRPPK AARTESADSA LGLDAHSDLE KPATSSDDGF EEPTPKPKPS
     KKTTTLPGPV SIIAQKKNKF RTDDAKNVKP PTLEEMKELR DTRNLFHSNL FKLQVKEMLE
     ELQLKTKYTE YIDNWMESFT VFTQRLKDGL VEKSQLEVPL NVDKKISGFI FSKPTKEPQL
     IGAASTGTLL GPKIVVDVAL EMPKDCLHKD DYLNLIYDQK RALYLTYVTN QMRSDPAYSQ
     DKFAFNYHGN NPLKPVLELT PAAKQVSKHL QLRLFITAPQ STFKPSRFVP WNNNIRPTYY
     NDEWDEEEAL PSTQHYNASV LFDLTLAQNQ ALLDKAFKGR RNFQDGLLLL KVWLRQRELD
     RGFTGFGSHI LASFIVYLNQ QRILHQSSSS YQVARTVWNQ LANTDWTNGI TLAPASGQTE
     QLSTMAGYYD VCFMDVSGQL NLCANVPLGV YQRVRAEAKL AVDLLNDMKL NSFPYIFMQK
     CPLYTRVDNI LKITNYSSIQ QMLVLHSKPQ MKYDFASYGY PQLLQILTEL LQKGLKQRVQ
     AILPIETVSS AWPVESKAPI IGQAIQLGLI LDPEHAYEVL DKGPSSNDDP EGSAEFRKFW
     GEKSNLRRFQ DGSITEAVVW GTTKDAPSKK RLIVRQIVMH LLEHHLQLDS KDIQYIAAEL
     DLVYQLSPWF KVSKVKTKLE LQQDTDAEAL SPNVIRCYDD LARQLHALDD LPLEIVSISS
     ISPVSRYCEP MPVLPQARMM ADHIHASHIQ RVIIQLGQSG KWPNELSALR ALKTAFLIEI
     GEKLKAQCRL NWSITSEGLL VLKRGFCFLL ELAHNKELAL LKQEVTERGV TKYVDNPESR
     ALEQRHYILP KVSGALHSLH QSHSAYGPTV LIAKRWLATQ LLDDGIWPPM ATELLVAHLY
     QQRNAPQAIA APQTGFIRFL HLLAHSDWNG ELFLLNFNSS WQEQQIGDLE HSFRSDRQSY
     PPLALATSYD QQHAGRLWTT GESPSLRILS HVSRLARHAL EMIETSLQSK DLRFVRPAQL
     FRGSSEGYDL VIQLKSDLVP NALSYDLGSP FVSFDQPNYL LPRAGKDPLA AIVHQLRSAY
     SDYAAFFYNP HGGKELAIMW RPPAVFAPKA FKVTELQACT LCDKGKVQVV RETLVEDFKV
     LLKDFYLRIS TPEELKREQR EHQNPKRYFN AKPQDNESCS KSKKRKLAKA AKVQAPLKRK
     SLIKSRPLKS LS
 
 
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