ID   NOL6_DROSE              Reviewed;        1196 AA.
AC   B4IBY3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE   AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN   Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GM15447;
OS   Drosophila sechellia (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7238;
RN   [1] {ECO:0000312|EMBL:EDW44891.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rob3c / Tucson 14021-0248.25 {ECO:0000312|EMBL:EDW44891.1};
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8R5K4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR   EMBL; CH480827; EDW44891.1; -; Genomic_DNA.
DR   RefSeq; XP_002041243.1; XM_002041207.1.
DR   AlphaFoldDB; B4IBY3; -.
DR   SMR; B4IBY3; -.
DR   STRING; 7238.B4IBY3; -.
DR   EnsemblMetazoa; FBtr0198432; FBpp0196924; FBgn0170365.
DR   GeneID; 6616913; -.
DR   KEGG; dse:6616913; -.
DR   HOGENOM; CLU_003502_0_1_1; -.
DR   OMA; NPHGGKE; -.
DR   PhylomeDB; B4IBY3; -.
DR   Proteomes; UP000001292; Unassembled WGS sequence.
DR   GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1196
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000383628"
FT   REGION          1..75
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1140..1196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..44
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1165..1179
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1196 AA;  136668 MW;  B6F16A32C7E4163B CRC64;
     MPGKLVGSSE EAARTGTQAN AHAEDHSDLE HSAPSTDDGF DEPKPPIAKS VPPSTAIPKK
     NNFKQRGNTK NVKPPTLEEM KELRDTQNLF HSNLFKLQVK EMLEELQLKQ KYTDFIENWL
     ESFTVFTRQL KDGLMERTHL EVPMKLSEKP TGFVFSKPTR EPYLIGAAAT GTLLGPKIVV
     DVALEMPKES LHKEDYLNLR YDQKRALYLT YVTERMMESP DYAQDQFNFN YYANNPLKPV
     LELIPVTKQV NKHLQVRLFI TAPLSSFKPG RFVPWNNNIR PSFYGDEWDE QDPLPSTQHY
     NANVLFDLTL SENQAQLDKA FKSRRNFQDG LLLLKVWLRQ RQLDIGYSGF GAHILAAFIV
     YLNKQRILHQ SSSSYQVART VWNQLANTDW TKGISLAVDP IQTEELNKFA EHYDVCFIDF
     TGQHNLCANI PLYLYKRVRE EAKLAVELLN DMKLNSFPLI FMQKCPLYSR VDNILKISNY
     SCINQMLTLH SQPRIKYDFA NYGYPQLLHL LTELLKKGLA ERVHSILPLE TATAAWPVEN
     KAPVIGKYIQ LGLILQPEHA YEVLNKGPAA NDDLAGAEEF RRFWGEKSNL RRFQDGSITE
     AVVWGTAQDS PAKKRLIVRH VVLHLLEHHL QLDSKEVQYI GGELDQVYKL SPWFKVNKLK
     TKLSLDQDTD AEALSPHVIR CYDELARQLH GLNDLPLEIV SISGVSPIFR YCEPQPVLPQ
     ALLVENRILA STIQRVVIQL GQSGKWPTEL GALRALKTAF LIEIGEKLEA QCRLHWVISA
     DGLLVLKQGY CFLIELAHNK ELALLKQEVT ERGITTYVDN AASRFLERQH YILPKVSGAL
     HSLHQTYSAF GSTVLLAKRW LATQLLDDGL WPDMATELLV AHLFQQRYAP QSIAAPQTGF
     IRFLQLLSHS DFNGELFLLN FNNSWQEQQI ADLEHNYRSN RQSYPPLAVA TSYDMQHAGR
     LWTSDQSPSQ RVLGHVTRLA RRALEIIETS LMSKDLRFVR PAQLFRASNE GYDLVIQFKP
     DLVPNSLSYD LGSPFVSFSQ PNFSLPRAGS DYIARIVGLL RSAYSDFAAF FYNPHGGKEL
     AIVWRPTTEF AAKPFKVTEL QACRPCGNGK VQVLKETLLE DFKLLLKDFY LRIATPEELK
     REQREHQKPM RYFEANQAVE ESKPKPKKHR KRKGTGKEAP PKKKRLIKSS TLKALK