ID   NOL6_DROSI              Reviewed;        1196 AA.
AC   B4QX57;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE   AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN   Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GD20301;
OS   Drosophila simulans (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7240;
RN   [1] {ECO:0000312|EMBL:EDX12711.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8R5K4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR   EMBL; CM000364; EDX12711.1; -; Genomic_DNA.
DR   AlphaFoldDB; B4QX57; -.
DR   SMR; B4QX57; -.
DR   STRING; 7240.B4QX57; -.
DR   PRIDE; B4QX57; -.
DR   EnsemblMetazoa; FBtr0220211; FBpp0218703; FBgn0191776.
DR   HOGENOM; CLU_003502_0_1_1; -.
DR   OMA; NPHGGKE; -.
DR   PhylomeDB; B4QX57; -.
DR   Proteomes; UP000000304; Chromosome 3r.
DR   Bgee; FBgn0191776; Expressed in embryo and 3 other tissues.
DR   GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1196
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000383629"
FT   REGION          1..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1140..1196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..44
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1165..1190
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1196 AA;  136434 MW;  4FC160CB3CB1B027 CRC64;
     MPGKLVGSSE EAARTGTQAN AHAEDHSDLE HSAPSTDDGF DEPKPPIAKS VPPSTAIPKK
     NNFKHRGDTK NVKPPTLEEM KELRDTQNLF HSNLFKLQVK EMLEELQLKQ KYTDFIENWL
     ESFTVFTRQL KDGLMERTHL EVPMKLSEKP TGFVFSKPTR EPYLIGAAAT GTLLGPKIVV
     DVALEMPKES LHKEDYLNLR YDQKRALYLT YVTERMMESQ NYAQDQFNFN YYANNPLKPV
     LELIPVTKQV NKHLQVRLFI TAPLSSFKPG RFVPWNNNIR PSFYGDEWDE QDPLPSTQHY
     NANVLFDLTL SENQAQLDKA FKSRRNFQDG LLLLKVWLRQ RQLDIGYSGF GAHILAAFIV
     YLNKQRILHQ SSSSYQVART VWNQLANTDW TKGISLAVDP IQTEELNKFA KHYDVCFIDF
     TGQHNLCANI PLYLYQRVRE EAKLAVELLN DMKLNSFPLI FMQKCPLYSR VDNILKISNY
     SCINQMLTLH SQPRIKYDFA NYGYPQLLHL LTELLKKGLA ERVHSILPLE TATAAWPVEN
     KAPVIGKYIQ LGLILQPEHA YEVLNKGPAA NDDPAGAEEF RRFWGEKSNL RRFQDGSITE
     AVVWGTAQDS PAKKRLIVRH IVLHLLEHHL QLDSKEVQYI GGELDQVYKL SPWFKVNKLK
     TKLSLDQDTD AEALSPHVIR CYDELARQLH GLNDLPLEIV SISGVSPIFR YCEPQPVLPQ
     ALLVENRILA STIQRVVIQL GQSGKWPTEL SALRALKTAF LIEIGEKLEA QCRLHWVISA
     DGLLVLKQGY CFLIELAHNK ELALLKQEVT ERGITTYVDN AASRFLERQH YILPKVSGAL
     HSLHQTYSAF GSTVLLAKRW LATQLLDDGL WPDMATELLV AHLFQQRYAP QSIAAPQTGF
     IRFLQLLSHS DFNGELFLLN FNNSWQEQQI ADLEHNYRSN RQSYPPLAVA TSYDMQHAGR
     LWTSDQSPSQ RVLGHVTRLA RRALEIIETS LMSKDLRFVR PAQLFRASNE GYDLVIQFKP
     DLVPNSLSYD LGSPFVSFSQ PNFSLPRAGS DYIARIVGLL RSAYSDFAAF FYNPHGGKEL
     AIVWRPTTEF AAKPFKVTEL QACSPSGNGK VQVLKETLLE DFKLLLKDFY LRIATPEELK
     REQREHQKPM RYFEANQAVA ESKPKPKKHG KRKGTGKAAP PKKKRLIKSS TLKALK