NOL6_DROVI
ID NOL6_DROVI Reviewed; 1184 AA.
AC B4LWT7;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 58.
DE RecName: Full=Nucleolar protein 6 {ECO:0000250|UniProtKB:Q9H6R4};
DE AltName: Full=Maternal transcript 89Ba {ECO:0000250|UniProtKB:Q8IH00};
GN Name=Mat89Ba {ECO:0000250|UniProtKB:Q8IH00}; ORFNames=GJ23506;
OS Drosophila virilis (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila.
OX NCBI_TaxID=7244;
RN [1] {ECO:0000312|EMBL:EDW66658.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tucson 15010-1051.87 {ECO:0000312|EMBL:EDW66658.1};
RX PubMed=17994087; DOI=10.1038/nature06341;
RG Drosophila 12 genomes consortium;
RT "Evolution of genes and genomes on the Drosophila phylogeny.";
RL Nature 450:203-218(2007).
CC -!- SUBUNIT: May be associated with rRNA. {ECO:0000250|UniProtKB:Q9H6R4}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q8R5K4}.
CC -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000255}.
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DR EMBL; CH940650; EDW66658.1; -; Genomic_DNA.
DR RefSeq; XP_002053138.1; XM_002053102.2.
DR AlphaFoldDB; B4LWT7; -.
DR SMR; B4LWT7; -.
DR STRING; 7244.FBpp0237923; -.
DR PRIDE; B4LWT7; -.
DR EnsemblMetazoa; FBtr0239431; FBpp0237923; FBgn0210604.
DR GeneID; 6630892; -.
DR KEGG; dvi:6630892; -.
DR eggNOG; KOG2054; Eukaryota.
DR HOGENOM; CLU_003502_0_1_1; -.
DR InParanoid; B4LWT7; -.
DR OMA; NPHGGKE; -.
DR OrthoDB; 176625at2759; -.
DR PhylomeDB; B4LWT7; -.
DR Proteomes; UP000008792; Unassembled WGS sequence.
DR GO; GO:0000794; C:condensed nuclear chromosome; ISS:UniProtKB.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR InterPro; IPR005554; NOL6/Upt22.
DR InterPro; IPR035082; Nrap_D1.
DR InterPro; IPR035367; Nrap_D2.
DR InterPro; IPR035368; Nrap_D3.
DR InterPro; IPR035369; Nrap_D4.
DR InterPro; IPR035370; Nrap_D5.
DR InterPro; IPR035371; Nrap_D6.
DR PANTHER; PTHR17972; PTHR17972; 1.
DR Pfam; PF03813; Nrap; 1.
DR Pfam; PF17403; Nrap_D2; 1.
DR Pfam; PF17404; Nrap_D3; 1.
DR Pfam; PF17405; Nrap_D4; 1.
DR Pfam; PF17406; Nrap_D5; 1.
DR Pfam; PF17407; Nrap_D6; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..1184
FT /note="Nucleolar protein 6"
FT /id="PRO_0000383630"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1133..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1184 AA; 134053 MW; 0A40DC9962EE7F0F CRC64;
MGRIKEKESK APSLSESHTD YEYAATAATS SDDGFDEPNR VPVHKRKVQL TNGEAKKKKF
KHADSNVKPP TLEEIKEIRD TRNLFHSNLF KLQVKEMLEE IQLKPKYSNY IETWIETFTI
TVQELKDGLL DTCELEVPLH LHKKSFNFQF LTPTSEPKLI GAAATGTLLG PKIVVDVALE
MPAACFQHDD YRNLIYDQKR ALYLATVASK IKQSPAFKAD QFAYNYHANN PLKPVLELTP
ASKLGKYLLL RVYITAQSEI FKLSRFLPWT NNIRPSVFGD KWNEAETLPA TQHYNANVLF
DLTLAENQKL LLSTFTGRRN FQEGLLLLKV WLRQRQLDVG FSGFSAHILA AYIAYLKQQR
LLHQSSSSYQ IARTVWNQLA NSDWTQGITL SQHQPHQLIT LAGYYDVCFM DVTGYYNLCA
NLPLAVYKAV CAEAKLAVEL LNDVKVNSFS HIFMQTSPLY TRMDNILKIT NPASVDQLLQ
LHVQPHVKYD YANYAHPQLL KLLTDLLQKG LGQRVHAILP LEVPCSPWTV DTKAPVIGRS
LTLGLILDPE HAHEVLDKGP ATNEDANGAA EFRKFWGNKS NLRRFQDGSI TEAVVWATAT
DAPSQKRLIV RQIVLYLLEH QLQLEPSEVQ YIAGNLDVVY SLTPSFKVAK LQTKLKIQQE
TDAEALTPNV IHCYDALARQ LHSLGDLPLD IVSISGISPV FRYCEPQPLL PQARLVSDRI
HAGQVLRVII QLGPSGKWPS DLGALRSLKT AFLIQIGQQL KEQHHLHWHL CKDGLLVLKQ
GYCFLLELAH SKELALLKQQ QTERGVTTYV DNPASRELER RHYILPRVSG ALHALHQMHG
AFGPTVLIAK RWLAAQLLDD GLWPSIATEL LVAHLFQQRQ TPHTTVSPQT GFIRFLQLLA
HSDWSGELFL LNFNNSWTEQ QITDLEHSYR SERDSYPSLC LATAYDQQHA GRLWTSNNSP
SKPVLGRVTL LARHALQLIE SSLLSPKLAF VRPAQLFMAS GDGYDLVIQL KPDLLSNTLC
YDLGSPFLPF SQRNFRLPLA GCDQLAKVVQ QLRDAYSEYA AFFYNPHGGK ELAIVWRPAS
EFAPKPFKVN ELQACTPCVG GKVQVDRDTL VEDFKLLLKD FYLRVCTPQE LKREQREHNK
PKRYFNGQGE SEPDKPQKKK KKASTIPTNA KKRLMKSKSM NALC