ID   NOL6_XENLA              Reviewed;        1147 AA.
AC   Q6NRY2;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 2.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Nucleolar protein 6;
GN   Name=nol6;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably associated with rRNA.
CC       {ECO:0000250|UniProtKB:Q9Y3A4}.
CC   -!- SUBUNIT: Interacts with RRP7A; required for NOL6 localization to
CC       nucleolus. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8R5K4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH70577.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC070577; AAH70577.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001084843.1; NM_001091374.1.
DR   AlphaFoldDB; Q6NRY2; -.
DR   SMR; Q6NRY2; -.
DR   PRIDE; Q6NRY2; -.
DR   DNASU; 431889; -.
DR   GeneID; 431889; -.
DR   KEGG; xla:431889; -.
DR   CTD; 431889; -.
DR   Xenbase; XB-GENE-994699; nol6.L.
DR   OrthoDB; 176625at2759; -.
DR   Proteomes; UP000186698; Chromosome 1L.
DR   Bgee; 431889; Expressed in testis and 19 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1147
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000215649"
FT   REGION          1..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1147 AA;  129852 MW;  69D8236F710D3FFA CRC64;
     MQKKRSRAGA AEQEAASDDG EMSDSSDKME VSQNKGKSGI KRAPEADDVL RPVKLSKSDL
     YKPPTNDELN RLKETENLFH TNLLRMQIEE LLQEVKLKEK RRKTIDGFLH EINALLGTIP
     ETPKTDLTDQ SWLSSSIKVP FLQVPYQVKG KFSFLPPSSI KVVGSYLLGT CIKPEINVDL
     AVTMPQEILQ VKDNLNQRYS RKRALYLAHI ASHLTDNKLF SSVKFTYMNS NHLKPILLLR
     PQGKDEKLVT VRIHICPPPG FFKLSRLYPN KNNVRTSWYT EQQTETEGVC DPPTPYYNNT
     ILSDLTLEHH LHHLTNCATD FPGMKDAIAL LKVWLHQRQL DKGFGCFNGF LASMLISYLL
     SKNKINKVMS GYQVLRNTLQ FLATTDLTVN GITMATCSDS SLPSLPDFHE AFQVVFVDPM
     GVVNLCADMT ASKYRQIQFE ASESLKVLDD TNVNGFHLLL MVPKPFVRTF DHVFHLTNVA
     KLQGTCKKMK LLNQLIDRGG DYLATALPYL LSVLSKGLGP RVSLLSHTLT HKPEWNVGEE
     PAKHKDSGLV TVGLLLDPEL YTNVLDKGPA ADSSEALDFR AFWGEKSELR RFQDGSICEA
     VVWTGGSLYD KRKVPELIVK YLLELHANIP ESCINYTGNA LDCVLSRGRE TSTEEEKMVS
     IIQSYDDLSR KLWNLNDLPL TITSVQGTHP CLRYTDVFPP LPVKPDWSSY HLLREKKCLI
     PNPEKPCPAY VSPVKVICHM EGSGKWPQDK DAIKRLKAAF QIRLSELLSS QHQLLCNPSA
     THTDVYKDGY VFRVQVAYHR EPQYMKEFVT PEGMLKYQDT EESMQLEMET NHLPHLSSTL
     HGLHQQHPAF GGTSRLAKRW IQSQLLGDSF SEECLDLLVA HLFLHPAPYS PPSSALVGFL
     RFLHLVATFD WKNSPLIVNL NGELKGSEYT EIQNDFISAR AQLPVMFIAT PKDKKDSVWT
     KNQPTAQMLQ RLIVLCLESL RALEQQLMDP RGNHDYKMIF RPPLDLYDVL IRLNPKQISR
     HREAVDQPAK SFFRGMLKEG AQVKDLMFPV VGYDPIQLFL QELREAYGEF ALFFHDLHGG
     DVIGVLWKPS SFEPQPFKTT NVKGRQMDGK SDKALLVPNA EAFVEDLEIL GEGLVAGVEA
     QTERWNI