ID   NOL6_XENTR              Reviewed;        1145 AA.
AC   Q5M7P5;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Nucleolar protein 6;
GN   Name=nol6;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably associated with rRNA.
CC       {ECO:0000250|UniProtKB:Q9Y3A4}.
CC   -!- SUBUNIT: Interacts with RRP7A; required for NOL6 localization to
CC       nucleolus. {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9H6R4}.
CC   -!- SIMILARITY: Belongs to the NRAP family. {ECO:0000305}.
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DR   EMBL; BC088522; AAH88522.1; -; mRNA.
DR   RefSeq; NP_001011358.1; NM_001011358.1.
DR   AlphaFoldDB; Q5M7P5; -.
DR   SMR; Q5M7P5; -.
DR   STRING; 8364.ENSXETP00000018226; -.
DR   DNASU; 496825; -.
DR   GeneID; 496825; -.
DR   KEGG; xtr:496825; -.
DR   CTD; 65083; -.
DR   Xenbase; XB-GENE-994692; nol6.
DR   eggNOG; KOG2054; Eukaryota.
DR   InParanoid; Q5M7P5; -.
DR   OrthoDB; 176625at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0032545; C:CURI complex; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0034456; C:UTP-C complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   GO; GO:0006409; P:tRNA export from nucleus; IBA:GO_Central.
DR   InterPro; IPR005554; NOL6/Upt22.
DR   InterPro; IPR035082; Nrap_D1.
DR   InterPro; IPR035367; Nrap_D2.
DR   InterPro; IPR035368; Nrap_D3.
DR   InterPro; IPR035369; Nrap_D4.
DR   InterPro; IPR035370; Nrap_D5.
DR   InterPro; IPR035371; Nrap_D6.
DR   PANTHER; PTHR17972; PTHR17972; 1.
DR   Pfam; PF03813; Nrap; 1.
DR   Pfam; PF17403; Nrap_D2; 1.
DR   Pfam; PF17404; Nrap_D3; 1.
DR   Pfam; PF17405; Nrap_D4; 1.
DR   Pfam; PF17406; Nrap_D5; 1.
DR   Pfam; PF17407; Nrap_D6; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..1145
FT                   /note="Nucleolar protein 6"
FT                   /id="PRO_0000215650"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1145 AA;  129374 MW;  634C9F5ABED57139 CRC64;
     MQKKRNRAGP PQQEAASDDG EMSDSSDKME VAQGKGKSAV KRAPDADEVL RPVKLSKSDL
     YKPPTNDELN RLKETEHLFH TNLLRMQIEE LLQEVKLKEK RRKTIDGFLR EINTLLGTIP
     ETPQTDLTDQ TWLPDSIKVP ILQVPYQVKG KFCFLPPSSI KVVGSYLLGT CIKPEINVDL
     AVTMPQEILQ AKDNLNQRYS RKRALYLAHI ASHLANNELF SSVKFTYMNS NHLKPVLLLR
     PYGKDEKLVT VRIHVCPPPG FFKISRLYPN KNNVRTAWYT EQETEGVNEP PTPHYNNTIL
     SDLTLEHHLH HLSNCASDFP GMKDAVALLK VWLHQRQLDK GYGCFNGFLA AMLISYLLSK
     NKINKVMSGY QVLRNTLQFL ATTDLTVNGI TMATSTDSSL PSLHDFHEAF QVVFVDPLGV
     VNLCADMTTN KYHQIQFEAR ESLKVLDDTS ADGFHLLLMV PKPFVRTFDH VFHLTNVSKL
     QGTCKKMKLL NQLIDQGGDY LATSLPYVLS ILSKGLGPRV ALLSHTLPHR PEWDIGEEPA
     KHRDSSLLSV GLLLEAELHT SVLEKGPAAD SSQALDFRAF WGEKSELRRF QDGSICEAVV
     WPGSSLCEKR KVPELIVKYL LELHADIPES CISYTGNVLD CVLTRGKEAG TEEEKMVGII
     QSYDDLSRKL WNLTDLPLTV TSVQGTHPCL RYSDVFPPLP VKPDWSSYQL LREKKCLVPN
     PEKPCPAYVA PVKVICHMEG SGKWPQDKDA IKRVKAAFQI RLAELLRAQH QLLCNPSATH
     TDVYKDGYVF RVQVAYHREP QYMKEIVTPE GMLKYQDTEE SLQLELETLH LPSLTSTLHG
     LHQQHPAFGG TSRMAKRWIH SQLLGDSFSE ECVDLLVAHL FLHPAPYSPP SSPQVGFLRF
     LHLLATFDWK NSPLIVNLNG ELKGPDYTEI QNDFISARAQ LPVMFIATPK DKKDSLWTKT
     QPTAQILQRL IVLCLESLRA LEQQLMDPSG SQDYKMTFRP PLDLYDILIR LNPKQIPRHR
     EAVDQPAKSF FRGLLKEGAQ VKDLMFPVVG YDPVQCYLQE LREAYGEFAL FFHDKHGGDV
     IGVLWKPSGF EPQPFKTTNM TGRVMDGKSA KPLLVPNVEA IVEDFEILGE GLVASVEART
     ERWSI