ID   NOLR_RHIML              Reviewed;         122 AA.
AC   P28267;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Nodulation protein NolR;
GN   Name=nolR;
OS   Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=382;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=41;
RX   PubMed=1840615; DOI=10.1016/0022-2836(91)90583-r;
RA   Kondorosi E., Pierre M., Cren M., Haumann U., Buire M., Hoffmann B.,
RA   Schell J., Kondorosi A.;
RT   "Identification of NolR, a negative transacting factor controlling the nod
RT   regulon in Rhizobium meliloti.";
RL   J. Mol. Biol. 222:885-896(1991).
CC   -!- FUNCTION: Negative transacting factor controlling the nod regulon. May
CC       control the expression of nodD1, nodD2, nodD3 and nodABC genes.
CC   -!- SUBUNIT: Binds to the operator site in homodimeric form.
CC   -!- MISCELLANEOUS: R.meliloti strain 1021 has a frameshift mutation in the
CC       nolR gene that disrupt the protein coding region.
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DR   EMBL; X59050; CAA41777.1; -; Genomic_DNA.
DR   PIR; S19675; S19675.
DR   AlphaFoldDB; P28267; -.
DR   SMR; P28267; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR001845; HTH_ArsR_DNA-bd_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01022; HTH_5; 1.
DR   PRINTS; PR00778; HTHARSR.
DR   SMART; SM00418; HTH_ARSR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50987; HTH_ARSR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Nodulation; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..122
FT                   /note="Nodulation protein NolR"
FT                   /id="PRO_0000160624"
FT   DOMAIN          15..109
FT                   /note="HTH arsR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00340"
FT   DNA_BIND        49..68
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00340"
SQ   SEQUENCE   122 AA;  13349 MW;  941AD34529F8113F CRC64;
     MNFRMEHTMQ PLPPEKHEDA EIAAGFLSAM ANPKRLLILD SLVKEEMAVG ALAHKVGLSQ
     SALSQHLSKL RAQNLVSTRR DAQTIYYSSS SDAVLKILGA LSDIYGDDTD AVEEKPLVRK
     SA