ID   NONA_DROLR              Reviewed;         698 AA.
AC   Q9GRX4;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Protein no-on-transient A;
GN   Name=nonA;
OS   Drosophila littoralis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=47316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=1007;
RA   Huttunen S., Campesan S., Hoikkala A.;
RT   "Intra- and interspecific nucleotide variation at the nonA gene in
RT   Drosophila littoralis and D. virilis.";
RL   Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for normal vision and courtship behavior in
CC       Drosophila. {ECO:0000250}.
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DR   EMBL; AJ296178; CAC14308.1; -; mRNA.
DR   AlphaFoldDB; Q9GRX4; -.
DR   SMR; Q9GRX4; -.
DR   FlyBase; FBgn0043410; Dlit\nonA.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012975; NOPS.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF08075; NOPS; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat; RNA-binding; Sensory transduction; Vision.
FT   CHAIN           1..698
FT                   /note="Protein no-on-transient A"
FT                   /id="PRO_0000081661"
FT   DOMAIN          281..353
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          355..441
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          515..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          597..698
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          484..582
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..193
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..247
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        516..571
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        626..689
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   698 AA;  75154 MW;  368E05164765781F CRC64;
     MENSVKMDTS GNSTPLPQRQ ARANNQPNKN IGKHGPQKQN EGASDGGPAE KRQRFGPNNQ
     NGGGGSVGGG GGGGGGSGGG GGGGGQNQNK NFANKGGFGG GGNRNRNRGG NQNRSNFQNQ
     NQNQKSTTDA PKADGGNLND KSNEANNANQ SNSNSAAQAQ AQLQAQAQAH AQAQAQAHAQ
     AQAQAQAQAH AHAQNQAFRA RGGGGGGGGG GGGGGGGGGG GRDRNRGSRG GGGGGQNSGG
     GNNSQRGDDF FIAQRLRSIS GPTHELPPIE VAQETKFSGR NRLYVGNLTN DITDEELREM
     FKPYGEIGEI FSNLEKNFTF LKVDYHINAE KAKRALDGSM RKGRQLRVRF APNATILRVS
     NLTPFVSNEL LYKSFEIFGP IERASITVDD RGKHLGEGTV EFAKKSSASA CLRLCNEKCF
     FLTASLRPCL VEPMEVNDDN DGLPEKALNK KLQEFNQERS VGPRFADLNS FEHEYGSRWK
     QLHDLFKSKQ DALKRELKME EEKLDAQMEY ARYGQETELS RQELRKRESD NERKKLEWEM
     REKQAEEMRK REEETMRRHQ TEMQSRMVRQ EEDMRRRQQE NTLFMQAQQL NSLLDQQEGF
     GGGNNGGGGG GGGGGGGVGG GVGNSNFDNF GGNSNSPFEV FRGNNNSSMA GNNAGPGANN
     QQQDSFAAFE FGVNNMNQGG NQRGNNGGNN VPWGRRRF