ID   NONA_DROVI              Reviewed;         697 AA.
AC   Q9GRW7;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Protein no-on-transient A;
GN   Name=nonA;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11156994; DOI=10.1093/genetics/157.2.751;
RA   Campesan S., Chalmers D., Sandrelli F., Megighian A., Peixoto A.A.,
RA   Costa R., Kyriacou C.P.;
RT   "Comparative analysis of the nonA region in Drosophila identifies a highly
RT   diverged 5' gene that may constrain nonA promoter evolution.";
RL   Genetics 157:751-764(2001).
CC   -!- FUNCTION: Required for normal vision and courtship behavior in
CC       Drosophila. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ298998; CAC10058.1; -; mRNA.
DR   AlphaFoldDB; Q9GRW7; -.
DR   SMR; Q9GRW7; -.
DR   STRING; 7244.FBpp0233210; -.
DR   PRIDE; Q9GRW7; -.
DR   eggNOG; KOG0115; Eukaryota.
DR   ChiTaRS; nonA; fly.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR012975; NOPS.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF08075; NOPS; 1.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil; Repeat; RNA-binding; Sensory transduction; Vision.
FT   CHAIN           1..697
FT                   /note="Protein no-on-transient A"
FT                   /id="PRO_0000081663"
FT   DOMAIN          285..357
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          359..445
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          551..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          601..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          488..586
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..187
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        625..688
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   697 AA;  75337 MW;  516BD031DA5FABFB CRC64;
     MENSVKMDNS GNSTPLPQRQ RRANNQPNKN IGKLGPQKQN EGASDGGPAE KRQRFGPNNQ
     NGGGGSVVGG GGGGGGGGGQ NQNKNFANKG GFGGGGNRNR NRGGNQNRSN FQNQNQNQKS
     TTDAPKADGG NLNDKSNEAN NANQSNSNSA AQAQAQLQAQ AQAHAQAQAQ AQAQAHAQAQ
     AQAHAHAQNQ AFRARGGGGG GGGGGGGGGG GGGGGGGGGG GGGGRDRNPD RRGGGGGGGQ
     NSGGGNNSQR GDDFFYSQRL RSISGPTHEL PPIEVAQETK FSGRNRLYVG NLTNDITDEE
     LREMFKPYGE IGEIFSNLEK NFTFLKVDYH INAEKAKRPL DGSMRKGRHV RVRFAPNATI
     LRVSNLTPFV SNELLYKSFE IFGPIERASI TVDDRGKHLG EGTVEFAKKS SASACLRLCN
     EKCFFLTASL RPCLVEPMEV NDDNDGLPEK ALNKKLQEFN QERSVGPRFA DLNSFEHEYG
     SRWKQLHDLF KSKQDALKRE LKMEEEKLDA QMEYARYEQE TELLRQELRK RESDNERKKL
     EWEMREKQAE EMRKREEETM RRHQTEMQSR MVRQEEDMRR RQQENTLFMQ AQQLNSLLDQ
     QEGFGGGNGG GGGGGGGGGG VGNSNFDNFG GNSNSPFEVF RGNNNSSMAG NNAGPGANNQ
     QQDSFAAFEF GVNNMNQGGN QRGNNGGNNV PWGRRRF