NOP10_DICDI
ID NOP10_DICDI Reviewed; 64 AA.
AC Q54J26;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=H/ACA ribonucleoprotein complex subunit 3;
DE AltName: Full=Nucleolar protein 10;
DE AltName: Full=Nucleolar protein family A member 3;
DE AltName: Full=snoRNP protein NOP10 homolog;
GN Name=nop10; Synonyms=nola3; ORFNames=DDB_G0288347;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- FUNCTION: Required for ribosome biogenesis. Part of the H/ACA small
CC nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes
CC pseudouridylation of rRNA (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA
CC snoRNP) complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP10 family. {ECO:0000305}.
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DR EMBL; AAFI02000111; EAL63270.1; -; Genomic_DNA.
DR RefSeq; XP_636775.1; XM_631683.1.
DR AlphaFoldDB; Q54J26; -.
DR SMR; Q54J26; -.
DR STRING; 44689.DDB0235394; -.
DR PaxDb; Q54J26; -.
DR EnsemblProtists; EAL63270; EAL63270; DDB_G0288347.
DR GeneID; 8626578; -.
DR KEGG; ddi:DDB_G0288347; -.
DR dictyBase; DDB_G0288347; nola3.
DR eggNOG; KOG3503; Eukaryota.
DR HOGENOM; CLU_184680_1_0_1; -.
DR InParanoid; Q54J26; -.
DR OMA; MYTLGPD; -.
DR PhylomeDB; Q54J26; -.
DR PRO; PR:Q54J26; -.
DR Proteomes; UP000002195; Chromosome 5.
DR GO; GO:0031429; C:box H/ACA snoRNP complex; IBA:GO_Central.
DR GO; GO:0090661; C:box H/ACA telomerase RNP complex; IBA:GO_Central.
DR GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; ISS:dictyBase.
DR GO; GO:0034513; F:box H/ACA snoRNA binding; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; ISS:dictyBase.
DR GO; GO:0070034; F:telomerase RNA binding; IBA:GO_Central.
DR GO; GO:0006364; P:rRNA processing; IC:dictyBase.
DR GO; GO:0031118; P:rRNA pseudouridine synthesis; IBA:GO_Central.
DR GO; GO:0031120; P:snRNA pseudouridine synthesis; IBA:GO_Central.
DR InterPro; IPR007264; H/ACA_rnp_Nop10.
DR InterPro; IPR036756; H/ACA_rnp_Nop10_sf.
DR PANTHER; PTHR13305; PTHR13305; 1.
DR Pfam; PF04135; Nop10p; 1.
DR SUPFAM; SSF144210; SSF144210; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..64
FT /note="H/ACA ribonucleoprotein complex subunit 3"
FT /id="PRO_0000328028"
SQ SEQUENCE 64 AA; 7631 MW; 9687E4CC0213B73A CRC64;
MHLMYYNDKD GQRVYTLKKE SPNHEATYSA HPARFSVDDK YSRERIALKK RFGLLLTQQP
PLEF