ID   NOP10_SCHPO             Reviewed;          64 AA.
AC   Q9P7M5;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit nop10;
DE   AltName: Full=Nucleolar protein 10;
DE   AltName: Full=Nucleolar protein family A member 3;
DE   AltName: Full=snoRNP protein nop10;
GN   Name=nop10; ORFNames=SPAP27G11.13c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Non-catalytic component of the H/ACA small nucleolar
CC       ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of
CC       rRNA and is required for ribosome biogenesis. This involves the
CC       isomerization of uridine such that the ribose is subsequently attached
CC       to C5, instead of the normal N1. Pseudouridine ('psi') residues may
CC       serve to stabilize the conformation of rRNAs. The H/ACA snoRNP complex
CC       also mediates pseudouridylation of other types of RNAs. The H/ACA
CC       snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
CC       {ECO:0000250|UniProtKB:Q6Q547}.
CC   -!- SUBUNIT: Component of the small nucleolar ribonucleoprotein particles
CC       containing H/ACA-type snoRNAs (H/ACA snoRNPs).
CC       {ECO:0000250|UniProtKB:Q6Q547}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q6Q547}.
CC   -!- SIMILARITY: Belongs to the NOP10 family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB76034.1; -; Genomic_DNA.
DR   RefSeq; NP_593418.1; NM_001018851.2.
DR   AlphaFoldDB; Q9P7M5; -.
DR   SMR; Q9P7M5; -.
DR   BioGRID; 279090; 66.
DR   STRING; 4896.SPAP27G11.13c.1; -.
DR   iPTMnet; Q9P7M5; -.
DR   MaxQB; Q9P7M5; -.
DR   PaxDb; Q9P7M5; -.
DR   EnsemblFungi; SPAP27G11.13c.1; SPAP27G11.13c.1:pep; SPAP27G11.13c.
DR   GeneID; 2542636; -.
DR   KEGG; spo:SPAP27G11.13c; -.
DR   PomBase; SPAP27G11.13c; nop10.
DR   VEuPathDB; FungiDB:SPAP27G11.13c; -.
DR   eggNOG; KOG3503; Eukaryota.
DR   HOGENOM; CLU_184680_1_0_1; -.
DR   InParanoid; Q9P7M5; -.
DR   OMA; ITRSAHP; -.
DR   PhylomeDB; Q9P7M5; -.
DR   PRO; PR:Q9P7M5; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0031429; C:box H/ACA snoRNP complex; ISO:PomBase.
DR   GO; GO:0090661; C:box H/ACA telomerase RNP complex; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0034513; F:box H/ACA snoRNA binding; ISO:PomBase.
DR   GO; GO:0019843; F:rRNA binding; IC:PomBase.
DR   GO; GO:0070034; F:telomerase RNA binding; IBA:GO_Central.
DR   GO; GO:0031118; P:rRNA pseudouridine synthesis; ISO:PomBase.
DR   GO; GO:0031120; P:snRNA pseudouridine synthesis; ISO:PomBase.
DR   InterPro; IPR007264; H/ACA_rnp_Nop10.
DR   InterPro; IPR036756; H/ACA_rnp_Nop10_sf.
DR   PANTHER; PTHR13305; PTHR13305; 1.
DR   Pfam; PF04135; Nop10p; 1.
DR   SUPFAM; SSF144210; SSF144210; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..64
FT                   /note="H/ACA ribonucleoprotein complex subunit nop10"
FT                   /id="PRO_0000149012"
SQ   SEQUENCE   64 AA;  7658 MW;  2F9C65BA310A437A CRC64;
     MHLMYYLNDE GKRVYTLKKV SPDGRVTKSS HPARFSPDDK YSRQRYTLKK RFHVLLTQLP
     AKPY