ID   NOP14_ASHGO             Reviewed;         806 AA.
AC   Q75A47;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable nucleolar complex protein 14;
GN   Name=NOP14; OrderedLocusNames=ADR072C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       Has a role in the nuclear export of 40S pre-ribosomal subunit to the
CC       cytoplasm (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP14 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51992.1; -; Genomic_DNA.
DR   RefSeq; NP_984168.1; NM_209521.1.
DR   AlphaFoldDB; Q75A47; -.
DR   SMR; Q75A47; -.
DR   STRING; 33169.AAS51992; -.
DR   EnsemblFungi; AAS51992; AAS51992; AGOS_ADR072C.
DR   GeneID; 4620317; -.
DR   KEGG; ago:AGOS_ADR072C; -.
DR   eggNOG; KOG2147; Eukaryota.
DR   HOGENOM; CLU_008874_0_0_1; -.
DR   InParanoid; Q75A47; -.
DR   OMA; KSKMHKY; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0030692; C:Noc4p-Nop14p complex; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR   GO; GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
DR   InterPro; IPR007276; Nop14.
DR   PANTHER; PTHR23183; PTHR23183; 1.
DR   Pfam; PF04147; Nop14; 2.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..806
FT                   /note="Probable nucleolar complex protein 14"
FT                   /id="PRO_0000137157"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          92..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          130..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          249..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          787..806
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..148
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..207
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   806 AA;  92040 MW;  5528B1FA7FAB696C CRC64;
     MAGSQLKRLR ATLKAHGLTG QTNVKKSKNR KTSKEYDHEE KARVVSAIRE QFNPFDVKAN
     RSKLHAAGAG DAKVAVGKPG ISKQIGEEQR LRFHESKKAQ KNRAGGLIDK RFGERNKHMT
     AEEIMLERFT KERQAQSRQS KKSLFNLDDE EDDGDASGAL THFGKPLASD FEDGDLGVGM
     AGALGPKRGL ADDEMEPEVP KKKTKAEVMK EVIAKSKFYK HERQKAREQM EEEIDQLDDE
     FEGIMSELRA APRARTNPVE SKPSQELEYD QKVRELCLDR RAAPADRVKT DEEMKQEREE
     KLKKLELDRV NRMNGLVDGE DAQGVEDLDN GFWEAEDSDA GEYGEYMEAI ADSDDDLKFE
     NEPETAEPTG TSHKQKKIAA LPCPITHAEL MDVLTAYQLE EQPHVVKNII KAYQPKLAEG
     NKEKLDKFSG VLLHHILFLS SSDYASQADV IVEVQNSLIS ILKLMSEKYN QALSEACRQV
     VTEIQQRFKA QHYLGLKPSD LVFFSLVGYI FSTSDHYHLV VTPCCILLGE FLEQIKLTDY
     ERLIFVAIAA NICVRYQRIS RRHVPELAYF LKRALASLLP FSTENSQAFN IRLDSDKLSL
     SKTLVLEDIE PTLKLRFLFL KEYDDSVQAQ LLVNLLSTLD ACVSQLWKGV SAFPELTQPF
     KPLLSAFASS YPTFAKPQQI MERMERISNL QQHFPLTLQN HKPAAIPSYM PKFEDNFNPE
     KKSYDPDRTR NDINKMKAQL KKERKLTMKE LRKDTKFEAR QKIEEQRKHA DDYKAKMARI
     VNQISTEEGA DKNKYEKEKR LRAGKR