NOP14_CANGA
ID NOP14_CANGA Reviewed; 799 AA.
AC Q6FNV1;
DT 07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Probable nucleolar complex protein 14;
GN Name=NOP14; OrderedLocusNames=CAGL0J08844g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Has a role in the nuclear export of 40S pre-ribosomal subunit to the
CC cytoplasm (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP14 family. {ECO:0000305}.
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DR EMBL; CR380956; CAG61044.1; -; Genomic_DNA.
DR RefSeq; XP_448093.1; XM_448093.1.
DR AlphaFoldDB; Q6FNV1; -.
DR SMR; Q6FNV1; -.
DR STRING; 5478.XP_448093.1; -.
DR PRIDE; Q6FNV1; -.
DR EnsemblFungi; CAG61044; CAG61044; CAGL0J08844g.
DR GeneID; 2889679; -.
DR KEGG; cgr:CAGL0J08844g; -.
DR CGD; CAL0133322; CAGL0J08844g.
DR VEuPathDB; FungiDB:CAGL0J08844g; -.
DR eggNOG; KOG2147; Eukaryota.
DR HOGENOM; CLU_008874_0_0_1; -.
DR InParanoid; Q6FNV1; -.
DR OMA; KSKMHKY; -.
DR Proteomes; UP000002428; Chromosome J.
DR GO; GO:0030692; C:Noc4p-Nop14p complex; IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0030515; F:snoRNA binding; ISS:UniProtKB.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:EnsemblFungi.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; ISS:UniProtKB.
DR InterPro; IPR007276; Nop14.
DR PANTHER; PTHR23183; PTHR23183; 2.
DR Pfam; PF04147; Nop14; 2.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..799
FT /note="Probable nucleolar complex protein 14"
FT /id="PRO_0000137158"
FT REGION 13..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..78
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 777..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..152
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 92531 MW; F5165E4A06F1204E CRC64;
MAGSQLKELK ATLKAHGLTG QTNVKKSKKG KREAKKYDHE EKARTIAKIR DRFNPFEVKT
TKNKRKGGDP GLLNSDRVAV GKPGISKQIG EEARRRAFEA KKLMKKRKGG VIDKRFGERD
KTLTEEEKML ERFTRERQAG SQRKKNLFNL EDDDEDGPIE LDMFGNKLTH LGESLSLADD
LNVQAEDTED LEEGQPQRKK TKLEVMKEII AKSKFHKQER QAAQRKLEDN IDELDEDFDD
VMAELMTTQT LKQDDIEVPA EEKDYDIKVK ELNLEKRAAP ADRTKTEEEL QKEAEERRQK
LEEQRLNRMQ GMLEDEEGEE RGVEDLDDGF WGSDSEVEEG ENIANSDEDI EVESSSEEAI
SYKSKKLVAI SCPQTHPEFL NDLKGLSLLE QPIHVKAIIK AYQPKLAEGN KVKLANFSKV
LLKHMIYLAN QRYDKDLIKF DKTQNEFLII LKRLSEKYNQ AISEVSREYI LDIQERFKKQ
NFHALNNGDI LFFIIVGVLF STSDQYHLVV TPAQIILCEF LEQIRFKSLK RIAVGSVLLR
IILQYQRLSK RYIPETVYFL QKALLSLVVN PDDIESDMTL PIRLDTFDCG LKLKEPSLPD
DAVVHLHELF TKSTTNEEDL KINVLSNLFE DLEKLIGSHW NNEAAFPEIC EIFEPILSVY
KVRYPSITTV ESIEEKIKRM KKLNKHYPLA LQAHRPTAIP SYAPKFEENF NPAKKSYDTD
VARNEVNKMK AQLKKERKFV MKELRKDTKF EARQRIDEKK KEAEAYHSKM SNIINTINTE
EGAEKNKYER EKRLRAGKK
