ID   NOP16_AJECN             Reviewed;         243 AA.
AC   A6RC73;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Nucleolar protein 16;
GN   Name=NOP16; ORFNames=HCAG_07231;
OS   Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC   unclassified Histoplasma.
OX   NCBI_TaxID=2059318;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NAm1 / WU24;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP16 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH476662; EDN10770.1; -; Genomic_DNA.
DR   RefSeq; XP_001537809.1; XM_001537759.1.
DR   AlphaFoldDB; A6RC73; -.
DR   SMR; A6RC73; -.
DR   STRING; 339724.A6RC73; -.
DR   EnsemblFungi; EDN10770; EDN10770; HCAG_07231.
DR   GeneID; 5444053; -.
DR   KEGG; aje:HCAG_07231; -.
DR   VEuPathDB; FungiDB:HCAG_07231; -.
DR   HOGENOM; CLU_078857_0_0_1; -.
DR   OMA; MQQTEAD; -.
DR   OrthoDB; 1431164at2759; -.
DR   Proteomes; UP000009297; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR019002; Ribosome_biogenesis_Nop16.
DR   PANTHER; PTHR13243; PTHR13243; 1.
DR   Pfam; PF09420; Nop16; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..243
FT                   /note="Nucleolar protein 16"
FT                   /id="PRO_0000320364"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          60..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   243 AA;  27477 MW;  ECB5311A9F1B72A0 CRC64;
     MGRILQKKKN RSGAPRVKQK SNRLKNGNKK INVLGNAIIA QNWDKKLTLT QNYRRLGLAS
     QLNAPTGGAE NKPDDPSNGR QEADSLHLLP SLASVKMIKP AEMRVERDPA TGKILRVIHP
     ENETEEVEIA GRKHRRANPL EDPLNEVGDD VLNNTALRIH GSSTSSAVVQ ALERQAALEE
     EALKKKQPRQ QSKREEEWLE RLVAKHGDNI IAMVRDTRLN PMQQTEGDIK RRLKKWREKR
     GNV