ID   NOP16_ASHGO             Reviewed;         236 AA.
AC   Q75AB6; Q8J1F3;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Nucleolar protein 16;
GN   Name=NOP16; OrderedLocusNames=ADR002W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-80.
RA   Wendland J., Dietrich F., Mohr C., Philippsen P.;
RT   "Isolation and functional analysis of centromeric DNA of the filamentous
RT   ascomycete Ashbya gossypii.";
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP16 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51922.1; -; Genomic_DNA.
DR   EMBL; AF384990; AAO16966.1; -; Genomic_DNA.
DR   RefSeq; NP_984098.1; NM_209451.1.
DR   AlphaFoldDB; Q75AB6; -.
DR   SMR; Q75AB6; -.
DR   STRING; 33169.AAS51922; -.
DR   EnsemblFungi; AAS51922; AAS51922; AGOS_ADR002W.
DR   GeneID; 4620246; -.
DR   KEGG; ago:AGOS_ADR002W; -.
DR   eggNOG; KOG4771; Eukaryota.
DR   HOGENOM; CLU_078857_0_0_1; -.
DR   InParanoid; Q75AB6; -.
DR   OMA; MQQTEAD; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR019002; Ribosome_biogenesis_Nop16.
DR   PANTHER; PTHR13243; PTHR13243; 1.
DR   Pfam; PF09420; Nop16; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..236
FT                   /note="Nucleolar protein 16"
FT                   /id="PRO_0000320365"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          89..118
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   236 AA;  27605 MW;  621EE5B5CAD8BDB3 CRC64;
     MASVRKRKMA RSSVRKVTRR NRDKQRKVNI ACNPIIEKNW DYNLTLAQNY KRLGLTAKLA
     PRAGGEEIDL SKVIQKSVPI CSAFEDYDSE SDVEQEKRNN DDALEDGEYD PAKIPEGEAR
     IQRDENGDVV KVVYGTMKTV DVDEDISELK QKLEQDKVKT EVVQELESYA SRPVNRRVRY
     QSSREEEWLG RLYEKHGEDY NSMARDLKLN IYQQSVGDLK RRMKKWLKAH HIDERQ