NOP16_CRYNB
ID NOP16_CRYNB Reviewed; 213 AA.
AC P0CP25; Q55UY2; Q5KL99;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Nucleolar protein 16;
GN Name=NOP16; OrderedLocusNames=CNBC6990;
OS Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS (Filobasidiella neoformans).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=283643;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B-3501A;
RX PubMed=15653466; DOI=10.1126/science.1103773;
RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT neoformans.";
RL Science 307:1321-1324(2005).
CC -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP16 family. {ECO:0000305}.
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DR EMBL; AAEY01000017; EAL21663.1; -; Genomic_DNA.
DR RefSeq; XP_776310.1; XM_771217.1.
DR AlphaFoldDB; P0CP25; -.
DR SMR; P0CP25; -.
DR EnsemblFungi; AAW42089; AAW42089; CNC00240.
DR EnsemblFungi; EAL21663; EAL21663; CNBC6990.
DR GeneID; 4935367; -.
DR KEGG; cnb:CNBC6990; -.
DR VEuPathDB; FungiDB:CNBC6990; -.
DR HOGENOM; CLU_078857_0_0_1; -.
DR Proteomes; UP000001435; Chromosome 3.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR019002; Ribosome_biogenesis_Nop16.
DR PANTHER; PTHR13243; PTHR13243; 1.
DR Pfam; PF09420; Nop16; 1.
PE 3: Inferred from homology;
KW Nucleus; Ribonucleoprotein; Ribosome biogenesis; rRNA processing.
FT CHAIN 1..213
FT /note="Nucleolar protein 16"
FT /id="PRO_0000410169"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..32
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 213 AA; 24390 MW; 5381A64FDB50EE4A CRC64;
MANPRQRNKA KSSRTQKPSL NAKRRMHQKL RKAPPLKGPE VLQEKWDKKK TVFQNYAALG
LLPSIPVSKG ASTSRSQRVK LPEVPAEAEA QNVKVGFGRI IRDEEGNVID IIIDEDEEKQ
EEEQIEVDEE KELEPVEAKT EVVKRLEELA ASAAPVKRHS SMSERTWLQQ LVDKYGDDTE
RMARDRKLNV WQKTEGEIKR MIKKAGGVQM LRK