ID   NOP16_CRYNJ             Reviewed;         213 AA.
AC   P0CP24; Q55UY2; Q5KL99;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Nucleolar protein 16;
GN   Name=NOP16; OrderedLocusNames=CNC00240;
OS   Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC
OS   MYA-565) (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=214684;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JEC21 / ATCC MYA-565;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Involved in the biogenesis of the 60S ribosomal subunit.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the pre-66S ribosomal particle. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP16 family. {ECO:0000305}.
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DR   EMBL; AE017343; AAW42089.1; -; Genomic_DNA.
DR   RefSeq; XP_569396.1; XM_569396.1.
DR   AlphaFoldDB; P0CP24; -.
DR   SMR; P0CP24; -.
DR   STRING; 5207.AAW42089; -.
DR   PaxDb; P0CP24; -.
DR   EnsemblFungi; AAW42089; AAW42089; CNC00240.
DR   GeneID; 3256640; -.
DR   KEGG; cne:CNC00240; -.
DR   VEuPathDB; FungiDB:CNC00240; -.
DR   eggNOG; KOG4771; Eukaryota.
DR   HOGENOM; CLU_078857_0_0_1; -.
DR   InParanoid; P0CP24; -.
DR   OMA; MQQTEAD; -.
DR   OrthoDB; 1431164at2759; -.
DR   Proteomes; UP000002149; Chromosome 3.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR019002; Ribosome_biogenesis_Nop16.
DR   PANTHER; PTHR13243; PTHR13243; 1.
DR   Pfam; PF09420; Nop16; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..213
FT                   /note="Nucleolar protein 16"
FT                   /id="PRO_0000320374"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..32
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   213 AA;  24390 MW;  5381A64FDB50EE4A CRC64;
     MANPRQRNKA KSSRTQKPSL NAKRRMHQKL RKAPPLKGPE VLQEKWDKKK TVFQNYAALG
     LLPSIPVSKG ASTSRSQRVK LPEVPAEAEA QNVKVGFGRI IRDEEGNVID IIIDEDEEKQ
     EEEQIEVDEE KELEPVEAKT EVVKRLEELA ASAAPVKRHS SMSERTWLQQ LVDKYGDDTE
     RMARDRKLNV WQKTEGEIKR MIKKAGGVQM LRK