NOP53_ARATH
ID NOP53_ARATH Reviewed; 442 AA.
AC O22892; Q93XZ8;
DT 26-SEP-2001, integrated into UniProtKB/Swiss-Prot.
DT 20-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Ribosome biogenesis protein NOP53 {ECO:0000305};
GN OrderedLocusNames=At2g40430; ORFNames=T2P4.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
CC -!- FUNCTION: May play a role in ribosome biogenesis.
CC {ECO:0000250|UniProtKB:Q9NZM5}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:Q9NZM5}. Nucleus, nucleoplasm
CC {ECO:0000250|UniProtKB:Q9NZM5}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=O22892-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the NOP53 family. {ECO:0000305}.
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DR EMBL; AC002336; AAB87593.2; -; Genomic_DNA.
DR EMBL; AC007020; AAM15353.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09827.1; -; Genomic_DNA.
DR EMBL; AY093264; AAM13263.1; -; mRNA.
DR EMBL; AY054491; AAK96682.1; -; mRNA.
DR PIR; D84829; D84829.
DR RefSeq; NP_565931.1; NM_129603.4. [O22892-1]
DR AlphaFoldDB; O22892; -.
DR BioGRID; 3974; 1.
DR STRING; 3702.AT2G40430.2; -.
DR iPTMnet; O22892; -.
DR PaxDb; O22892; -.
DR PRIDE; O22892; -.
DR ProteomicsDB; 238255; -. [O22892-1]
DR EnsemblPlants; AT2G40430.1; AT2G40430.1; AT2G40430. [O22892-1]
DR GeneID; 818636; -.
DR Gramene; AT2G40430.1; AT2G40430.1; AT2G40430. [O22892-1]
DR KEGG; ath:AT2G40430; -.
DR Araport; AT2G40430; -.
DR eggNOG; KOG2823; Eukaryota.
DR HOGENOM; CLU_048046_1_0_1; -.
DR InParanoid; O22892; -.
DR OMA; WRKTDIQ; -.
DR PhylomeDB; O22892; -.
DR PRO; PR:O22892; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22892; baseline and differential.
DR Genevisible; O22892; AT.
DR GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR GO; GO:0005654; C:nucleoplasm; ISS:UniProtKB.
DR GO; GO:0008097; F:5S rRNA binding; IBA:GO_Central.
DR GO; GO:0000027; P:ribosomal large subunit assembly; ISS:UniProtKB.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR InterPro; IPR011687; Nop53/GLTSCR2.
DR PANTHER; PTHR14211; PTHR14211; 3.
DR Pfam; PF07767; Nop53; 2.
DR PIRSF; PIRSF017302; Gltscr2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..442
FT /note="Ribosome biogenesis protein NOP53"
FT /id="PRO_0000218963"
FT REGION 242..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 442 AA; 50162 MW; E7065F9FA2ED18B1 CRC64;
MGKRSKTSRK GKKAWRANIS SEDIEDFFEK TTRDALSGGN LSAAPSEDLF HVDKSHDLPV
KRKIEKHRER VLRVDSILKK NPFVQLVPSS KPKLKKSKKT IVIEDKAPKQ VQKSVGDDSV
MADLWGDDSK GEHESNPRKI FKNPSIISAV EIEHPGCSYN PTTESHQDML AEAVAQEMQK
VYKTELGPAP VPLTIEGDTL SEDERYFLDV DNFSEGEDNE NVENEVSEAG IKLKENPFVQ
LKPSSNTNLK KIEDKTPRQA QKSVGDDSVM VDLLGDDIKE DLKYFLEVGN VGEGEDNKDV
KIEVSEAGNN VSRKTKRVTR VELNKRCRQK ALRKKETKEK AKEKILNEID SLPNILEEIA
KEDEDKQNKH LRRVIAKQEV LKIRPPRLGK YKFEAPPVQV LLTEEMTGSL RKLKACCTLA
RDRFKSLEKR GILVPSKQIR RF
