NOP56_CAEEL
ID NOP56_CAEEL Reviewed; 486 AA.
AC Q21276;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Nucleolar protein 56 {ECO:0000312|WormBase:K07C5.4};
GN Name=nol-56 {ECO:0000312|WormBase:K07C5.4};
GN ORFNames=K07C5.4 {ECO:0000312|WormBase:K07C5.4};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Required for 60S ribosomal subunit synthesis.
CC {ECO:0000250|UniProtKB:Q12460}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000250|UniProtKB:O00567}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR EMBL; BX284605; CAA94897.1; -; Genomic_DNA.
DR PIR; T23405; T23405.
DR RefSeq; NP_505660.1; NM_073259.7.
DR AlphaFoldDB; Q21276; -.
DR SMR; Q21276; -.
DR BioGRID; 44472; 11.
DR STRING; 6239.K07C5.4; -.
DR EPD; Q21276; -.
DR PaxDb; Q21276; -.
DR PeptideAtlas; Q21276; -.
DR EnsemblMetazoa; K07C5.4.1; K07C5.4.1; WBGene00010627.
DR GeneID; 179442; -.
DR KEGG; cel:CELE_K07C5.4; -.
DR UCSC; K07C5.4; c. elegans.
DR CTD; 179442; -.
DR WormBase; K07C5.4; CE06114; WBGene00010627; nol-56.
DR eggNOG; KOG2573; Eukaryota.
DR GeneTree; ENSGT00940000153534; -.
DR HOGENOM; CLU_015495_4_0_1; -.
DR InParanoid; Q21276; -.
DR OMA; DNYMFAK; -.
DR OrthoDB; 632707at2759; -.
DR PhylomeDB; Q21276; -.
DR Reactome; R-CEL-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR PRO; PR:Q21276; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00010627; Expressed in adult organism and 3 other tissues.
DR GO; GO:0031428; C:box C/D RNP complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.246.90; -; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP5_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; PTHR10894; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; SSF89124; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..486
FT /note="Nucleolar protein 56"
FT /id="PRO_0000219033"
FT DOMAIN 298..416
FT /note="Nop"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT REGION 450..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..486
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 54511 MW; 4DCBE5D88B56B116 CRC64;
MSEVPHFVLY EHAAGYALMK IKEFDDAGLI LQEVDAAHAD GYKFSQIVEL ASFDPFKNTE
AALENCNSIS EGLAHPDLTN FLQKSLPKKK KHVVLGINDS KLAGSLTEAF PDLKLVFGGV
ITEILRGTRV HFERLAKNLP HHSLSKAQLS LGHSYSRSKV KFDVHRVDNM VIQSIALLDQ
LDKDINLFGM RIREWYSYHY PELFRLAPDQ YKYSRLAVAI LDRNKMAENE NLENEILEIL
DNDSEKTAQI IEAARTSMGM DISDLDLENI KRFAARVSSL MEYRQQLHEY IKDRMDHCAP
SLSALIGEQV GARLISHAGS LTNLAKYPAS TVQILGAEKA LFRALKTRSN TPKYGLLFHS
SFIGKAGTKN KGRVSRYLAN KCSIAARVDC FSETPVSTYG EFLRQQVEDR LEYFTSGTVP
KKNIDVMKEA EEAAVEVKEK VIKKKKKAAK KAKRLAEESV TATAEAEVDE DAPKPKKKKK
SKAGDE
