ID   NOP58_ASPTN             Reviewed;         577 AA.
AC   Q0CQH1;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Nucleolar protein 58;
GN   Name=nop58; ORFNames=ATEG_04063;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR   EMBL; CH476598; EAU35865.1; -; Genomic_DNA.
DR   RefSeq; XP_001213241.1; XM_001213241.1.
DR   AlphaFoldDB; Q0CQH1; -.
DR   SMR; Q0CQH1; -.
DR   STRING; 341663.Q0CQH1; -.
DR   PRIDE; Q0CQH1; -.
DR   EnsemblFungi; EAU35865; EAU35865; ATEG_04063.
DR   GeneID; 4318188; -.
DR   VEuPathDB; FungiDB:ATEG_04063; -.
DR   eggNOG; KOG2572; Eukaryota.
DR   HOGENOM; CLU_015495_5_0_1; -.
DR   OMA; MGMRSNW; -.
DR   OrthoDB; 632707at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0031428; C:box C/D RNP complex; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR   GO; GO:0017069; F:snRNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000494; P:box C/D RNA 3'-end processing; IEA:EnsemblFungi.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:1902570; P:protein localization to nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0000452; P:snoRNA guided rRNA 2'-O-methylation; IEA:EnsemblFungi.
DR   Gene3D; 1.10.246.90; -; 1.
DR   InterPro; IPR045056; Nop56/Nop58.
DR   InterPro; IPR012974; NOP5_N.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   PANTHER; PTHR10894; PTHR10894; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF08156; NOP5NT; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; SSF89124; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..577
FT                   /note="Nucleolar protein 58"
FT                   /id="PRO_0000350977"
FT   DOMAIN          285..410
FT                   /note="Nop"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT   REGION          445..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..467
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..577
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  63072 MW;  53F0535742192BEF CRC64;
     MTLFILTETS AGYALLKAKD KKLLKRDDLS TETATPEGVS NLLKLKSFQK FDSAATALEE
     VASLVEGKVT PRLAGLLDEI KDEKKVSLAV ADPKLGNAIG KLPGLDIQLV ADSTTTDIYR
     AIREHLPTLI PGLLPQDMST MSLGLSHSLA RHKLKFSPDK IDTMIVQAIA LLDDLDKELN
     NYAMRVKEWY GWHFPELAKI LNDNIAYAKL VLKMGMRSNF ESADLAEILP EEIEGAVKAA
     ADRSMGTEIS QEDLENIQAL AEQVVGFSEY RQQLASYLTA RMNAIAPNLT ALVGELVGAR
     LIAHAGSLTN LSKSPASTLQ ILGAEKALFR ALKTKHDTPK YGLIYHASLI GQATGKNKGK
     MARVLAAKAS LGLRVDALAE WDDDVTEEDK AALGTEARFN LERKLAAMEG KPLKPRGVAI
     APNGTPAQPK KFDINEARKY NADADAMVDD EPKSAKKQKK LVEEVQDEEM ADANGASDSD
     SSEEESSKKS KKGKSDLEKM AEKAGLSVKR YQRKLERGEI EFDAEGNPTA VSKKDLKKAK
     KEAKKASKGD DKKRKRSDEG EGVDNAEKKK KKKKKDE