ID   NOP58_BOTFB             Reviewed;         568 AA.
AC   A6RMY5;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Nucleolar protein 58;
GN   Name=nop58; ORFNames=BC1G_01807;
OS   Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=332648;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B05.10;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR   EMBL; CH476846; EDN28688.1; -; Genomic_DNA.
DR   RefSeq; XP_001559651.1; XM_001559601.1.
DR   AlphaFoldDB; A6RMY5; -.
DR   SMR; A6RMY5; -.
DR   GeneID; 5440281; -.
DR   KEGG; bfu:BCIN_05g05790; -.
DR   VEuPathDB; FungiDB:Bcin05g05790; -.
DR   OMA; MGMRSNW; -.
DR   OrthoDB; 632707at2759; -.
DR   GO; GO:0031428; C:box C/D RNP complex; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR   GO; GO:0017069; F:snRNA binding; IEA:EnsemblFungi.
DR   GO; GO:0000494; P:box C/D RNA 3'-end processing; IEA:EnsemblFungi.
DR   GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR   GO; GO:1902570; P:protein localization to nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0000452; P:snoRNA guided rRNA 2'-O-methylation; IEA:EnsemblFungi.
DR   Gene3D; 1.10.246.90; -; 1.
DR   InterPro; IPR045056; Nop56/Nop58.
DR   InterPro; IPR012974; NOP5_N.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   PANTHER; PTHR10894; PTHR10894; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF08156; NOP5NT; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; SSF89124; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   3: Inferred from homology;
KW   Nucleus; Ribonucleoprotein; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..568
FT                   /note="Nucleolar protein 58"
FT                   /id="PRO_0000350978"
FT   DOMAIN          285..417
FT                   /note="Nop"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT   REGION          451..568
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..480
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        488..561
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   568 AA;  61264 MW;  9B33DBE6E88A7587 CRC64;
     MAPLFILTET AAGLVLFKAD KKLLKKDDVA SEIETAEGIN GLLKLKQFQK FDSAATALEE
     VASLVEGKVS PMLASLLDTL KDEKKASLAV ADPKLGQAIN KLPGLTLTPI SDSKTNDIFR
     GIRDHLPSLI PGLLPEHIST MSLGLSHSLS RHKLKFSPDK VDTMIVQAIS LLDDLDKELN
     TYAMRVKEWY GWHFPEMGKI VNDNLAYARV ILKVGMRVNT SSTDLADILP EEIETAIKAA
     AEVSMGTEIT QEDLDNIKLL AEQVVGFTEY RQQLSSYLSA RMQAIAPNLT ELVGDLVGAR
     LIAHAGSLMN LAKSPASTIQ ILGAEKALFR ALKTKHDTPK YGLIYHASLV GQATGKNKGK
     IARMLAAKAA IGLRVDALSD WSAQGEGKGD DVDDEERSAL GVTSRAKIER HLRGLEGKPL
     LPRGVAVGPN GKATSAPGKW EVKEARKYNA DADGLAGDEP AAAVPIREKK NKKLIEEVAE
     ESGSDSSDDS DASEKKPKKG DKEAKKAEKA AKKAEKAAKK AAKEAKKAAK AEKEAKKSDA
     PEVNGSKKRK SEDDGEKSEK KKKKKSKD