ID   NOP58_DEBHA             Reviewed;         517 AA.
AC   Q6BIX6;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Nucleolar protein 58;
GN   Name=NOP58; OrderedLocusNames=DEHA2G06842g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR   EMBL; CR382139; CAG90306.2; -; Genomic_DNA.
DR   RefSeq; XP_461845.2; XM_461845.1.
DR   AlphaFoldDB; Q6BIX6; -.
DR   SMR; Q6BIX6; -.
DR   STRING; 4959.XP_461845.2; -.
DR   EnsemblFungi; CAG90306; CAG90306; DEHA2G06842g.
DR   GeneID; 2904724; -.
DR   KEGG; dha:DEHA2G06842g; -.
DR   VEuPathDB; FungiDB:DEHA2G06842g; -.
DR   eggNOG; KOG2572; Eukaryota.
DR   HOGENOM; CLU_015495_5_2_1; -.
DR   InParanoid; Q6BIX6; -.
DR   OMA; MGMRSNW; -.
DR   OrthoDB; 632707at2759; -.
DR   Proteomes; UP000000599; Chromosome G.
DR   GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR   GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.246.90; -; 1.
DR   InterPro; IPR045056; Nop56/Nop58.
DR   InterPro; IPR012974; NOP5_N.
DR   InterPro; IPR042239; Nop_C.
DR   InterPro; IPR002687; Nop_dom.
DR   InterPro; IPR036070; Nop_dom_sf.
DR   InterPro; IPR012976; NOSIC.
DR   PANTHER; PTHR10894; PTHR10894; 1.
DR   Pfam; PF01798; Nop; 1.
DR   Pfam; PF08156; NOP5NT; 1.
DR   SMART; SM00931; NOSIC; 1.
DR   SUPFAM; SSF89124; SSF89124; 1.
DR   PROSITE; PS51358; NOP; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..517
FT                   /note="Nucleolar protein 58"
FT                   /id="PRO_0000350983"
FT   DOMAIN          283..403
FT                   /note="Nop"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT   REGION          423..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          456..517
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        447..509
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   517 AA;  57584 MW;  187FAE83EF59A306 CRC64;
     MAYVLTETAA GYALLKASDK KIYKSSSLIE DLNTVEKVTE QFKIHRFEKF SSAANALEEA
     NAIIEGRISD NLKKMLEDVK NDKKATLIVS EAKLGNAINK LGLNFSVVSD AASLDLHRAI
     KEFLPELLPG LDDSALKQMS LGLAHSMGRH KLKFSADKVD TMIVQAIALL DDLDKELNTY
     AMRCKEWYGW HFPELAKMIT DSVAYARIIL TMGIRSNAAD TDLSEILPEE AEEQVKSAAE
     VSMGTEITDI DLENIKALAE QIVDFAAYRE QLSNYLSSRM KAIAPNLTAL VGELVGARLI
     AHSGSLTSLA KAPASTIQIL GAEKALFRAL KTKHDTPKYG LLYHASLVGQ ASGKNKGKIA
     RVLAAKAAVA LRYDSLAEDR DDSGDFGLSV RTKVESRLSA LEGRDLRTTA KVIREQPKVD
     ITEARAYNAD ADAPMADADS DDESETEEEP KKEKKDKKEK KDKKEKKDKK DKKRKREEDD
     EEEEEDSKKS KKEKKEKKEK KDKKEKKDKK EKKKEKK