NOP58_PICST
ID NOP58_PICST Reviewed; 515 AA.
AC A3LUT0;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Nucleolar protein 58;
GN Name=NOP58; ORFNames=PICST_72477;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules
CC (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family. {ECO:0000305}.
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DR EMBL; CP000499; ABN66645.1; -; Genomic_DNA.
DR RefSeq; XP_001384674.1; XM_001384637.1.
DR AlphaFoldDB; A3LUT0; -.
DR SMR; A3LUT0; -.
DR STRING; 4924.XP_001384674.1; -.
DR EnsemblFungi; ABN66645; ABN66645; PICST_72477.
DR GeneID; 4839579; -.
DR KEGG; pic:PICST_72477; -.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_2_1; -.
DR InParanoid; A3LUT0; -.
DR OMA; MGMRSNW; -.
DR OrthoDB; 632707at2759; -.
DR Proteomes; UP000002258; Chromosome 5.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.246.90; -; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP5_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; PTHR10894; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; SSF89124; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..515
FT /note="Nucleolar protein 58"
FT /id="PRO_0000350990"
FT DOMAIN 283..403
FT /note="Nop"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00690"
FT REGION 423..515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..502
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 515 AA; 57281 MW; 97B889AF31A4CAA5 CRC64;
MAYVLTETAA GYALLKASDK KIHKSSSLIE DLNTADKVAE QFKIHRFEKF QSAANALEEA
NAVIEGRVSD SLKKMLEDAK SDKKATLIVS EAKLGNAINK LGLNFSVVSD AASLDLHRAI
REFLPELLPG LDDSMLKQMS LGLAHSIGRH KLKFSADKVD TMIVQAIALL DDLDKELNTY
AMRCKEWYGW HFPELAKMIV DSVAYARIIL TMGVRSNASE TDLSEILPEE LEEQVKSAAE
VSMGTEITAI DLENIRALAE QIVDFAAYRE QLSNYLSSRM KAIAPNLTAL VGELVGARLI
AHAGSLTSLA KAPASTIQIL GAEKALFRAL KTKHDTPKYG LLYHASLVGQ ASGKNKGKIA
RVLAAKAAVA LRYDSLAEER DDSGDFGLEV RAKVESRLSA LEGRDLRTTS KVVREQPKVD
ITEARAYNAD ADAPTAEVDS DDESDTEEID TKKEKKEKKE KKEKKDKKRK REDDDEEEED
KKSKKEKKEK KEKKEKKEKK EKKDKKDKKS KKEKK
